Pilot study of a commercialized human papillomavirus (HPV) genotyping assay

Comparison of HPV risk group to cytology and histology

Philip E. Castle, Mark Sadorra, Francisco Garcia, E. Blair Holladay, Janet Kornegay

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noacaranogenic types > negative specimens) with increasing severities of cytologic interpretations (PTrend < 0.0005) and histologic diagnoses (PTrend < 0.0005).

Original languageEnglish (US)
Pages (from-to)3915-3917
Number of pages3
JournalJournal of Clinical Microbiology
Volume44
Issue number11
DOIs
StatePublished - Nov 2006
Externally publishedYes

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Cell Biology
Histology
Human papillomavirus 16
Genotype
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Pilot study of a commercialized human papillomavirus (HPV) genotyping assay : Comparison of HPV risk group to cytology and histology. / Castle, Philip E.; Sadorra, Mark; Garcia, Francisco; Holladay, E. Blair; Kornegay, Janet.

In: Journal of Clinical Microbiology, Vol. 44, No. 11, 11.2006, p. 3915-3917.

Research output: Contribution to journalArticle

Castle, Philip E. ; Sadorra, Mark ; Garcia, Francisco ; Holladay, E. Blair ; Kornegay, Janet. / Pilot study of a commercialized human papillomavirus (HPV) genotyping assay : Comparison of HPV risk group to cytology and histology. In: Journal of Clinical Microbiology. 2006 ; Vol. 44, No. 11. pp. 3915-3917.
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