Pilot Analysis of Early Lactobacillus rhamnosus GG for Infant Colic Prevention

Michael D. Cabana, Michelle McKean, Amy L. Beck, Valerie Flaherman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We conducted a secondary analysis of data from a trial of Lactobacillus rhamnosus GG (LGG) supplementation as a pilot study to assess whether LGG prevents infant colic. For the first 6 months of life, infants received a daily dose of 10 billion colony-forming units of LGG or a control (n = 184). We compared the likelihood of a diagnosis of colic before 4 months of age, based on parent-reported symptoms or a physician diagnosis of colic. Out of the 184 infants, 18 (9.8%) had colic. There were no differences between the 2 groups in the percentage of infants with colic based on symptoms (control 5.4% vs LGG 9.8%; P = 0.19); physician diagnosis (control 3.2% vs LGG 7.6%; P = 0.26); or either symptoms or diagnosis combined (control 6.5% vs LGG 13.0%; P = 0.13). In this pilot study, early infant LGG supplementation does not appear to prevent the later development of colic.

Original languageEnglish (US)
Pages (from-to)17-19
Number of pages3
JournalJournal of pediatric gastroenterology and nutrition
Volume68
Issue number1
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

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Lactobacillus rhamnosus
Colic
Physicians

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology

Cite this

Pilot Analysis of Early Lactobacillus rhamnosus GG for Infant Colic Prevention. / Cabana, Michael D.; McKean, Michelle; Beck, Amy L.; Flaherman, Valerie.

In: Journal of pediatric gastroenterology and nutrition, Vol. 68, No. 1, 01.01.2019, p. 17-19.

Research output: Contribution to journalArticle

Cabana, Michael D. ; McKean, Michelle ; Beck, Amy L. ; Flaherman, Valerie. / Pilot Analysis of Early Lactobacillus rhamnosus GG for Infant Colic Prevention. In: Journal of pediatric gastroenterology and nutrition. 2019 ; Vol. 68, No. 1. pp. 17-19.
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