Pharmacotherapy of diabetes mellitus: Implications for the prevention and treatment of cardiovascular disease

Enzo Ragucci, Joel Zonszein, William H. Frishman

Research output: Contribution to journalReview article

1 Scopus citations


Diabetes mellitus in adults is associated with an increased risk of premature vascular disease and a higher mortality rate. The presence of other risk factors, often seen in diabetic patients, such as systemic hypertension, augments the rate of vascular diseases. Evidence is growing that tight control of hyperglycemia using insulin and/or oral hypoglycemic agents will modify this risk. More aggressive control of concomitant hypertension and/or hyperlipidemia is also required. Diabetic patients who have myocardial infarctions do worse than nondiabetic patients. Various strategies to improve outcomes include the use of tight blood glucose control, and various coronary interventions are currently under clinical study.

Original languageEnglish (US)
Pages (from-to)18-33
Number of pages16
JournalHeart Disease
Issue number1
Publication statusPublished - Jan 1 2003


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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