Pharmacotherapy of diabetes mellitus

Implications for the prevention and treatment of cardiovascular disease

Enzo Ragucci, Joel Zonszein, William H. Frishman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Diabetes mellitus in adults is associated with an increased risk of premature vascular disease and a higher mortality rate. The presence of other risk factors, often seen in diabetic patients, such as systemic hypertension, augments the rate of vascular diseases. Evidence is growing that tight control of hyperglycemia using insulin and/or oral hypoglycemic agents will modify this risk. More aggressive control of concomitant hypertension and/or hyperlipidemia is also required. Diabetic patients who have myocardial infarctions do worse than nondiabetic patients. Various strategies to improve outcomes include the use of tight blood glucose control, and various coronary interventions are currently under clinical study.

Original languageEnglish (US)
Pages (from-to)18-33
Number of pages16
JournalHeart Disease
Volume5
Issue number1
StatePublished - Jan 2003

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Diabetes Mellitus
Cardiovascular Diseases
Vascular Diseases
Drug Therapy
Hypertension
Hyperlipidemias
Hypoglycemic Agents
Hyperglycemia
Blood Glucose
Therapeutics
Myocardial Infarction
Insulin
Mortality
Clinical Studies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Pharmacotherapy of diabetes mellitus : Implications for the prevention and treatment of cardiovascular disease. / Ragucci, Enzo; Zonszein, Joel; Frishman, William H.

In: Heart Disease, Vol. 5, No. 1, 01.2003, p. 18-33.

Research output: Contribution to journalArticle

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