Pharmacotherapy of cryptococcosis

Michele Ritter, David L. Goldman

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Cryptococcus neoformans is an opportunistic fungal pathogen that causes central nervous system and pulmonary disease among immunocompromised patients. Recent studies highlight the high incidence of cryptococcosis among patients in certain resource-poor areas, where there is also a high incidence of AIDS. Despite the availability of antifungal agents with anticryptococcal activity, the mortality and treatment-failure rates associated with cryptococcosis remain unacceptably high. This article reviews current treatment strategies and the basis for these strategies, as well as prospects for future approaches to the treatment of cryptococcosis.

Original languageEnglish (US)
Pages (from-to)2433-2443
Number of pages11
JournalExpert Opinion on Pharmacotherapy
Volume10
Issue number15
DOIs
StatePublished - Oct 2009

Keywords

  • Antifungal
  • Cryptococcosis
  • Meningitis
  • Pneumonia

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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