pH, EF-1α and the cytoskeleton

Gang Liu, Brian T. Edmonds, John S. Condeelis

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

One of the unexpected cellular components found interacting with the cytoskeleton is elongation factor 1 alpha (EF-1α). How this interaction is regulated is not clear, but pH may be a potent regulator. Interestingly, pH also regulates the amount of protein translation occurring in many cell systems. In this paper, the authors suggest that sequestration of EF-1α in the cytoskeleton may play a key role in regulating the spatial distribution of macromolecular assembly in a way that is dependent on cytoplasmic pH.

Original languageEnglish (US)
Pages (from-to)168-171
Number of pages4
JournalTrends in Cell Biology
Volume6
Issue number5
DOIs
StatePublished - May 1996

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Peptide Elongation Factor 1
Cytoskeleton
Protein Biosynthesis

ASJC Scopus subject areas

  • Cell Biology

Cite this

pH, EF-1α and the cytoskeleton. / Liu, Gang; Edmonds, Brian T.; Condeelis, John S.

In: Trends in Cell Biology, Vol. 6, No. 5, 05.1996, p. 168-171.

Research output: Contribution to journalArticle

Liu, Gang ; Edmonds, Brian T. ; Condeelis, John S. / pH, EF-1α and the cytoskeleton. In: Trends in Cell Biology. 1996 ; Vol. 6, No. 5. pp. 168-171.
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