PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis

Jelena Radulovic; Vilma Gabbay

doi:10.1016/j.xcrm.2021.100282

PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis

Research output: Contribution to journal › Article › peer-review

Abstract

Vanderplow et al.¹ report decreased PFC Akt-mTOR signaling in males with bipolar disorder (BD) without psychosis compared with those with psychosis, possibly related to cognitive deficits. Understanding how cognition differs between these BD subtypes clinically and biologically remains a challenge.

Original language	English (US)
Article number	100282
Journal	Cell Reports Medicine
Volume	2
Issue number	5
DOIs	https://doi.org/10.1016/j.xcrm.2021.100282
State	Published - May 18 2021

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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title = "PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis",

abstract = "Vanderplow et al.1 report decreased PFC Akt-mTOR signaling in males with bipolar disorder (BD) without psychosis compared with those with psychosis, possibly related to cognitive deficits. Understanding how cognition differs between these BD subtypes clinically and biologically remains a challenge.",

author = "Jelena Radulovic and Vilma Gabbay",

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AB - Vanderplow et al.1 report decreased PFC Akt-mTOR signaling in males with bipolar disorder (BD) without psychosis compared with those with psychosis, possibly related to cognitive deficits. Understanding how cognition differs between these BD subtypes clinically and biologically remains a challenge.

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JO - Cell Reports Medicine

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PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis

Abstract

ASJC Scopus subject areas

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