TY - JOUR
T1 - Perspectives from the Society for Pediatric Research
T2 - Probiotic use in urinary tract infections, atopic dermatitis, and antibiotic-associated diarrhea: an overview
AU - Forster, Catherine S.
AU - Hsieh, Michael H.
AU - Cabana, Michael D.
N1 - Publisher Copyright:
© 2020, The Author(s).
PY - 2021/8
Y1 - 2021/8
N2 - Probiotics have received significant attention within both the scientific and lay communities for their potential health-promoting properties, including the treatment or prevention of various conditions in children. In this article, we review the published data on use of specific probiotic strains for three common pediatric conditions: the prevention of urinary tract infections and antibiotic-associated diarrhea and the treatment of atopic dermatitis. Research into the utility of specific probiotic strains is of varying quality, and data are often derived from small studies and case series. We discuss the scientific merit of these studies, their overall findings regarding the utility of probiotics for these indications, issues in reporting of methods, and results from these clinical trials, as well as future areas of investigation.
AB - Probiotics have received significant attention within both the scientific and lay communities for their potential health-promoting properties, including the treatment or prevention of various conditions in children. In this article, we review the published data on use of specific probiotic strains for three common pediatric conditions: the prevention of urinary tract infections and antibiotic-associated diarrhea and the treatment of atopic dermatitis. Research into the utility of specific probiotic strains is of varying quality, and data are often derived from small studies and case series. We discuss the scientific merit of these studies, their overall findings regarding the utility of probiotics for these indications, issues in reporting of methods, and results from these clinical trials, as well as future areas of investigation.
UR - http://www.scopus.com/inward/record.url?scp=85097236935&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85097236935&partnerID=8YFLogxK
U2 - 10.1038/s41390-020-01298-1
DO - 10.1038/s41390-020-01298-1
M3 - Article
C2 - 33288875
AN - SCOPUS:85097236935
SN - 0031-3998
VL - 90
SP - 315
EP - 327
JO - Pediatric Research
JF - Pediatric Research
IS - 2
ER -