Personality disorders and the trimensional personality questionnaire factors in major depressive disorder

Amy Farabaugh, Dost Ongur, Maurizio Fava, Sarah K. Hamill, Alana M. Burns, Jonathan E. Alpert

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We assessed the potential relationship between personality disorder (PD) clusters, as assessed by the SCID-II, and temperamental traits assessed by the Tridimensional Personality Questionnaire (TPQ) among a well-characterized, unmedicated cohort of outpatients with major depressive disorder (MDD). The TPQ and SCID-II were administered to 263 depressed outpatients (mean age = 39.9 ± 10.5 years; women = 139, 53%; initial 17-item Hamilton Rating Scale for Depression = 19.6 ± 3.4) who currently met criteria for MDD and who were enrolled in an 8-week treatment trial. The multiple linear regression method was used to evaluate the relationship between TPQ factors and personality disorder clusters, controlling for age, gender, and initial 17-item Hamilton Rating Scale for Depression score as necessary. Among outpatients with MDD, meeting criteria for a Cluster A PD diagnosis was related to high harm avoidance (HA) scores, as well as low reward dependence and novelty seeking (NS) scores. Additionally, high HA scores were associated with meeting criteria for a Cluster C PD diagnosis, while high NS scores were associated with meeting criteria for a Cluster B PD diagnosis. Certain temperament traits, especially HA and NS, appear to be associated with specific patterns of personality clusters among depressed patients.

Original languageEnglish (US)
Pages (from-to)747-750
Number of pages4
JournalJournal of Nervous and Mental Disease
Volume193
Issue number11
DOIs
StatePublished - Nov 2005
Externally publishedYes

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Personality Disorders
Major Depressive Disorder
Personality
Outpatients
Depression
Temperament
Reward
Linear Models
Surveys and Questionnaires

Keywords

  • Depression
  • Personality disorders
  • Temperament
  • TPQ

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Personality disorders and the trimensional personality questionnaire factors in major depressive disorder. / Farabaugh, Amy; Ongur, Dost; Fava, Maurizio; Hamill, Sarah K.; Burns, Alana M.; Alpert, Jonathan E.

In: Journal of Nervous and Mental Disease, Vol. 193, No. 11, 11.2005, p. 747-750.

Research output: Contribution to journalArticle

Farabaugh, Amy ; Ongur, Dost ; Fava, Maurizio ; Hamill, Sarah K. ; Burns, Alana M. ; Alpert, Jonathan E. / Personality disorders and the trimensional personality questionnaire factors in major depressive disorder. In: Journal of Nervous and Mental Disease. 2005 ; Vol. 193, No. 11. pp. 747-750.
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