Permeability and structure of junctional membranes at an electrotonic synapse

B. W. Payton, Michael V. L. Bennett, G. D. Pappas

Research output: Contribution to journalArticle

206 Citations (Scopus)

Abstract

The dye Procion Yellow M4RS crosses junctional membranes from cytoplasm to cytoplasm at electrotonic synapses between segments of the crayfish septate axon. The dye does not enter the cells from extracellular space. Thus permeability of junctional membranes is qualitatively digerent from that of nonjunctional membranes. Electron microscopy after fixation in the presence of lanthanum hydroxide indicates that these synapses are "gap junctions" and that there is a network of channels continuous with extracellular space between apposed junctional membranes. These channels must be interlaced with intercytoplasmic channels that are not open to extracellular space.

Original languageEnglish (US)
Pages (from-to)1641-1643
Number of pages3
JournalScience
Volume166
Issue number3913
StatePublished - 1969

Fingerprint

Electrical Synapses
Permeability
Extracellular Space
Membranes
Cytoplasm
Coloring Agents
Astacoidea
Gap Junctions
Synapses
Axons
Electron Microscopy

ASJC Scopus subject areas

  • General

Cite this

Permeability and structure of junctional membranes at an electrotonic synapse. / Payton, B. W.; Bennett, Michael V. L.; Pappas, G. D.

In: Science, Vol. 166, No. 3913, 1969, p. 1641-1643.

Research output: Contribution to journalArticle

Payton, BW, Bennett, MVL & Pappas, GD 1969, 'Permeability and structure of junctional membranes at an electrotonic synapse', Science, vol. 166, no. 3913, pp. 1641-1643.
Payton, B. W. ; Bennett, Michael V. L. ; Pappas, G. D. / Permeability and structure of junctional membranes at an electrotonic synapse. In: Science. 1969 ; Vol. 166, No. 3913. pp. 1641-1643.
@article{f54a130292c444789e2cc35eadab699f,
title = "Permeability and structure of junctional membranes at an electrotonic synapse",
abstract = "The dye Procion Yellow M4RS crosses junctional membranes from cytoplasm to cytoplasm at electrotonic synapses between segments of the crayfish septate axon. The dye does not enter the cells from extracellular space. Thus permeability of junctional membranes is qualitatively digerent from that of nonjunctional membranes. Electron microscopy after fixation in the presence of lanthanum hydroxide indicates that these synapses are {"}gap junctions{"} and that there is a network of channels continuous with extracellular space between apposed junctional membranes. These channels must be interlaced with intercytoplasmic channels that are not open to extracellular space.",
author = "Payton, {B. W.} and Bennett, {Michael V. L.} and Pappas, {G. D.}",
year = "1969",
language = "English (US)",
volume = "166",
pages = "1641--1643",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "3913",

}

TY - JOUR

T1 - Permeability and structure of junctional membranes at an electrotonic synapse

AU - Payton, B. W.

AU - Bennett, Michael V. L.

AU - Pappas, G. D.

PY - 1969

Y1 - 1969

N2 - The dye Procion Yellow M4RS crosses junctional membranes from cytoplasm to cytoplasm at electrotonic synapses between segments of the crayfish septate axon. The dye does not enter the cells from extracellular space. Thus permeability of junctional membranes is qualitatively digerent from that of nonjunctional membranes. Electron microscopy after fixation in the presence of lanthanum hydroxide indicates that these synapses are "gap junctions" and that there is a network of channels continuous with extracellular space between apposed junctional membranes. These channels must be interlaced with intercytoplasmic channels that are not open to extracellular space.

AB - The dye Procion Yellow M4RS crosses junctional membranes from cytoplasm to cytoplasm at electrotonic synapses between segments of the crayfish septate axon. The dye does not enter the cells from extracellular space. Thus permeability of junctional membranes is qualitatively digerent from that of nonjunctional membranes. Electron microscopy after fixation in the presence of lanthanum hydroxide indicates that these synapses are "gap junctions" and that there is a network of channels continuous with extracellular space between apposed junctional membranes. These channels must be interlaced with intercytoplasmic channels that are not open to extracellular space.

UR - http://www.scopus.com/inward/record.url?scp=0014692227&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0014692227&partnerID=8YFLogxK

M3 - Article

VL - 166

SP - 1641

EP - 1643

JO - Science

JF - Science

SN - 0036-8075

IS - 3913

ER -