Peripheral nerve blocks and trigger point injections in headache management - A systematic review and suggestions for future research

Avi Ashkenazi, Andrew Blumenfeld, Uri Napchan, Samer Narouze, Brian Grosberg, Robert Nett, Traci DePalma, Barbara Rosenthal, Stewart Tepper, Richard B. Lipton

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Interventional procedures such as peripheral nerve blocks (PNBs) and trigger point injections (TPIs) have long been used in the treatment of various headache disorders. There are, however, little data on their efficacy for the treatment of specific headache syndromes. Moreover, there is no widely accepted agreement among headache specialists as to the optimal technique of injection, type, and doses of the local anesthetics used, and injection regimens. The role of corticosteroids in this setting is also debated. We performed a PubMed search of the literature to find studies on PNBs and TPIs for headache treatment. We classified the abstracted studies based on the procedure performed and the treated condition. We found few controlled studies on the efficacy of PNBs for headaches, and virtually none on the use of TPIs for this indication. The most widely examined procedure in this setting was greater occipital nerve block, with the majority of studies being small and non-controlled. The techniques, as well as the type and doses of local anesthetics used for nerve blockade, varied greatly among studies. The specific conditions treated also varied, and included both primary (eg, migraine, cluster headache) and secondary (eg, cervicogenic, posttraumatic) headache disorders. Trigeminal (eg, supraorbital) nerve blocks were used in few studies. Results were generally positive, but should be taken with reservation given the methodological limitations of the available studies. The procedures were generally well tolerated. Evidently, there is a need to perform more rigorous clinical trials to clarify the role of PNBs and TPIs in the management of various headache disorders, and to aim at standardizing the techniques used for the various procedures in this setting.

Original languageEnglish (US)
Pages (from-to)943-952
Number of pages10
JournalHeadache
Volume50
Issue number6
DOIs
StatePublished - 2010

Fingerprint

Trigger Points
Nerve Block
Peripheral Nerves
Headache
Headache Disorders
Injections
Local Anesthetics
Post-Traumatic Headache
Cluster Headache
Migraine Disorders
PubMed
Adrenal Cortex Hormones
Clinical Trials
Therapeutics

Keywords

  • Headache management
  • Peripheral nerve blocks
  • Systematic review
  • Trigger point injections

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Peripheral nerve blocks and trigger point injections in headache management - A systematic review and suggestions for future research. / Ashkenazi, Avi; Blumenfeld, Andrew; Napchan, Uri; Narouze, Samer; Grosberg, Brian; Nett, Robert; DePalma, Traci; Rosenthal, Barbara; Tepper, Stewart; Lipton, Richard B.

In: Headache, Vol. 50, No. 6, 2010, p. 943-952.

Research output: Contribution to journalArticle

Ashkenazi, A, Blumenfeld, A, Napchan, U, Narouze, S, Grosberg, B, Nett, R, DePalma, T, Rosenthal, B, Tepper, S & Lipton, RB 2010, 'Peripheral nerve blocks and trigger point injections in headache management - A systematic review and suggestions for future research', Headache, vol. 50, no. 6, pp. 943-952. https://doi.org/10.1111/j.1526-4610.2010.01675.x
Ashkenazi, Avi ; Blumenfeld, Andrew ; Napchan, Uri ; Narouze, Samer ; Grosberg, Brian ; Nett, Robert ; DePalma, Traci ; Rosenthal, Barbara ; Tepper, Stewart ; Lipton, Richard B. / Peripheral nerve blocks and trigger point injections in headache management - A systematic review and suggestions for future research. In: Headache. 2010 ; Vol. 50, No. 6. pp. 943-952.
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