Abstract
We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 578-592 |
| Number of pages | 15 |
| Journal | Transplantation |
| Volume | 102 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 2018 |
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ASJC Scopus subject areas
- Transplantation
Cite this
Perioperative coagulation management in liver transplant recipients. / Bezinover, Dmitri; Dirkmann, Daniel; Findlay, James; Guta, Cosmin; Hartmann, Matthias; Nicolau-Raducu, Ramona; Mukhtar, Ahmed M.; Moguilevitch, Marina; Pivalizza, Evan; Rosenfeld, David; Saner, Fuat; Wray, Christopher; Wagener, Gebhard; West, James.
In: Transplantation, Vol. 102, No. 4, 01.04.2018, p. 578-592.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Perioperative coagulation management in liver transplant recipients
AU - Bezinover, Dmitri
AU - Dirkmann, Daniel
AU - Findlay, James
AU - Guta, Cosmin
AU - Hartmann, Matthias
AU - Nicolau-Raducu, Ramona
AU - Mukhtar, Ahmed M.
AU - Moguilevitch, Marina
AU - Pivalizza, Evan
AU - Rosenfeld, David
AU - Saner, Fuat
AU - Wray, Christopher
AU - Wagener, Gebhard
AU - West, James
PY - 2018/4/1
Y1 - 2018/4/1
N2 - We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.
AB - We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.
UR - http://www.scopus.com/inward/record.url?scp=85044770441&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044770441&partnerID=8YFLogxK
U2 - 10.1097/TP.0000000000002092
DO - 10.1097/TP.0000000000002092
M3 - Review article
VL - 102
SP - 578
EP - 592
JO - Transplantation
JF - Transplantation
SN - 0041-1337
IS - 4
ER -