Perioperative coagulation management in liver transplant recipients

Dmitri Bezinover; Daniel Dirkmann; James Findlay; Cosmin Guta; Matthias Hartmann; Ramona Nicolau-Raducu; Ahmed M. Mukhtar; Marina Moguilevitch; Evan Pivalizza; David Rosenfeld; Fuat Saner; Christopher Wray; Gebhard Wagener; James West

doi:10.1097/TP.0000000000002092

Perioperative coagulation management in liver transplant recipients

Dmitri Bezinover, Daniel Dirkmann, James Findlay, Cosmin Guta, Matthias Hartmann, Ramona Nicolau-Raducu, Ahmed M. Mukhtar, Marina Moguilevitch, Evan Pivalizza, David Rosenfeld, Fuat Saner, Christopher Wray, Gebhard Wagener, James West

Anesthesiology

Research output: Contribution to journal › Review article › peer-review

52 Scopus citations

Abstract

We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.

Original language	English (US)
Pages (from-to)	578-592
Number of pages	15
Journal	Transplantation
Volume	102
Issue number	4
DOIs	https://doi.org/10.1097/TP.0000000000002092
State	Published - Apr 1 2018

ASJC Scopus subject areas

Transplantation

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title = "Perioperative coagulation management in liver transplant recipients",

abstract = "We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.",

author = "Dmitri Bezinover and Daniel Dirkmann and James Findlay and Cosmin Guta and Matthias Hartmann and Ramona Nicolau-Raducu and Mukhtar, {Ahmed M.} and Marina Moguilevitch and Evan Pivalizza and David Rosenfeld and Fuat Saner and Christopher Wray and Gebhard Wagener and James West",

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T1 - Perioperative coagulation management in liver transplant recipients

AU - Bezinover, Dmitri

AU - Dirkmann, Daniel

AU - Findlay, James

AU - Guta, Cosmin

AU - Hartmann, Matthias

AU - Nicolau-Raducu, Ramona

AU - Mukhtar, Ahmed M.

AU - Moguilevitch, Marina

AU - Pivalizza, Evan

AU - Rosenfeld, David

AU - Saner, Fuat

AU - Wray, Christopher

AU - Wagener, Gebhard

AU - West, James

PY - 2018/4/1

Y1 - 2018/4/1

N2 - We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.

AB - We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.

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VL - 102

SP - 578

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JO - Transplantation

JF - Transplantation

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ER -

Perioperative coagulation management in liver transplant recipients

Abstract

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