Perioperative coagulation management in liver transplant recipients

Dmitri Bezinover; Daniel Dirkmann; James Findlay; Cosmin Guta; Matthias Hartmann; Ramona Nicolau-Raducu; Ahmed M. Mukhtar; Marina Moguilevitch; Evan Pivalizza; David Rosenfeld; Fuat Saner; Christopher Wray; Gebhard Wagener; James West

doi:10.1097/TP.0000000000002092

Perioperative coagulation management in liver transplant recipients

Dmitri Bezinover, Daniel Dirkmann, James Findlay, Cosmin Guta, Matthias Hartmann, Ramona Nicolau-Raducu, Ahmed M. Mukhtar, Marina Moguilevitch, Evan Pivalizza, David Rosenfeld, Fuat Saner, Christopher Wray, Gebhard Wagener, James West

Anesthesiology

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Abstract

We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.

Original language	English (US)
Pages (from-to)	578-592
Number of pages	15
Journal	Transplantation
Volume	102
Issue number	4
DOIs	https://doi.org/10.1097/TP.0000000000002092
State	Published - Apr 1 2018

ASJC Scopus subject areas

Transplantation

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10.1097/TP.0000000000002092

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Perioperative coagulation management in liver transplant recipients. / Bezinover, Dmitri; Dirkmann, Daniel; Findlay, James; Guta, Cosmin; Hartmann, Matthias; Nicolau-Raducu, Ramona; Mukhtar, Ahmed M.; Moguilevitch, Marina; Pivalizza, Evan; Rosenfeld, David; Saner, Fuat; Wray, Christopher; Wagener, Gebhard; West, James.

In: Transplantation, Vol. 102, No. 4, 01.04.2018, p. 578-592.

Research output: Contribution to journal › Review article › peer-review

Bezinover, Dmitri ; Dirkmann, Daniel ; Findlay, James ; Guta, Cosmin ; Hartmann, Matthias ; Nicolau-Raducu, Ramona ; Mukhtar, Ahmed M. ; Moguilevitch, Marina ; Pivalizza, Evan ; Rosenfeld, David ; Saner, Fuat ; Wray, Christopher ; Wagener, Gebhard ; West, James. / Perioperative coagulation management in liver transplant recipients. In: Transplantation. 2018 ; Vol. 102, No. 4. pp. 578-592.

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AU - Nicolau-Raducu, Ramona

AU - Mukhtar, Ahmed M.

AU - Moguilevitch, Marina

AU - Pivalizza, Evan

AU - Rosenfeld, David

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AU - Wray, Christopher

AU - Wagener, Gebhard

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AB - We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.

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Perioperative coagulation management in liver transplant recipients

Abstract

ASJC Scopus subject areas

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