Perfusion imaging by un-inverted flow-sensitive alternating inversion recovery (UNFAIR)

J. A. Helpern, Craig A. Branch, M. N. Yongbi, N. C. Huang

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

A new pulse sequence for estimating cerebral blood flow called UNFAIR, which uses a combination of sequential hyperbolic secant preparatory pulses, is introduced. This sequence is based on the same generalized conditions as previously introduced inversion recovery techniques except that the spins in the image slice of interest always have +z magnetization and the in-flowing spins are alternately inverted and uninverted. CBF-weighted images of rat brain under conditions of normocpnia and hypercapnia are presented and demonstrate the expected CBF response. A model describing the signal response to this pulse sequence is also presented and compared with in-vivo data acquired from gray and white matter.

Original languageEnglish (US)
Pages (from-to)135-139
Number of pages5
JournalMagnetic Resonance Imaging
Volume15
Issue number2
DOIs
StatePublished - 1997
Externally publishedYes

Fingerprint

Cerebrovascular Circulation
Perfusion Imaging
Hypercapnia
recovery
inversions
Imaging techniques
Recovery
hypercapnia
Brain
pulses
Rats
Magnetization
Blood
blood flow
rats
brain
estimating
magnetization
Gray Matter
White Matter

Keywords

  • Cerebral blood flow
  • Magnetic Resonance Imaging
  • Perfusion

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Perfusion imaging by un-inverted flow-sensitive alternating inversion recovery (UNFAIR). / Helpern, J. A.; Branch, Craig A.; Yongbi, M. N.; Huang, N. C.

In: Magnetic Resonance Imaging, Vol. 15, No. 2, 1997, p. 135-139.

Research output: Contribution to journalArticle

Helpern, J. A. ; Branch, Craig A. ; Yongbi, M. N. ; Huang, N. C. / Perfusion imaging by un-inverted flow-sensitive alternating inversion recovery (UNFAIR). In: Magnetic Resonance Imaging. 1997 ; Vol. 15, No. 2. pp. 135-139.
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