TY - JOUR
T1 - Percutaneous valve replacement in a young adult for radiation-induced aortic stenosis
AU - Latib, Azeem
AU - Montorfano, Matteo
AU - Figini, Filippo
AU - Maisano, Francesco
AU - Chieffo, Alaide
AU - Benussi, Stefano
AU - Bellanca, Raimondo
AU - Gerli, Chiara
AU - Spagnolo, Pietro
AU - Alfieri, Ottavio
AU - Colombo, Antonio
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012/6
Y1 - 2012/6
N2 - A 46-year-old woman known with relapsing Hodgkin's lymphoma diagnosed at age 5, treated with repeated cycles of radiotherapy and chemotherapy, presented with severe symptomatic radiation-induced aortic stenosis. She also had other late sequelae of radiotherapy including thyroid cancer, mediastinal fribrosis and left pulmonary fibrosis with severe restrictive lung disease and a newly diagnosed renal carcinoma. Due to the prohibitively high surgical risk and need for urgent treatment, she underwent successful transcatheter aortic valve replacement with transfemoral implantation of a 23 mm Edwards SAPIEN-XT prosthesis, which was performed without valvuloplasty of the noncalcified fibrotic valve. The final result was excellent with reduction of the transaortic gradient and no residual aortic regurgitation.
AB - A 46-year-old woman known with relapsing Hodgkin's lymphoma diagnosed at age 5, treated with repeated cycles of radiotherapy and chemotherapy, presented with severe symptomatic radiation-induced aortic stenosis. She also had other late sequelae of radiotherapy including thyroid cancer, mediastinal fribrosis and left pulmonary fibrosis with severe restrictive lung disease and a newly diagnosed renal carcinoma. Due to the prohibitively high surgical risk and need for urgent treatment, she underwent successful transcatheter aortic valve replacement with transfemoral implantation of a 23 mm Edwards SAPIEN-XT prosthesis, which was performed without valvuloplasty of the noncalcified fibrotic valve. The final result was excellent with reduction of the transaortic gradient and no residual aortic regurgitation.
KW - radiation-induced aortic stenosis
KW - small aortic annulus
KW - transcatheter aortic valve implantation
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U2 - 10.2459/JCM.0b013e3283517c4a
DO - 10.2459/JCM.0b013e3283517c4a
M3 - Article
C2 - 22450861
AN - SCOPUS:84861142159
SN - 1558-2027
VL - 13
SP - 397
EP - 398
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
IS - 6
ER -