TY - JOUR
T1 - Percutaneous treatment of non-paroxysmal atrial fibrillation
T2 - A paradigm shift from pulmonary vein to non-pulmonary vein trigger ablation?
AU - Della Rocca, Domenico G.
AU - Mohanty, Sanghamitra
AU - Trivedi, Chintan
AU - Di Biase, Luigi
AU - Natale, Andrea
N1 - Publisher Copyright:
© Radcliffe Cardiology 2018.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Pulmonary vein antrum isolation is the most effective rhythm control strategy in patients with paroxysmal AF. However, catheter ablation of non-paroxysmal AF has a lower success rate, even when persistent isolation of pulmonary veins (PVs) is achieved. As a result of arrhythmia-related electophysiological and structural changes in the atria, sites other than the PVs can harbour triggers. These non-PV triggers contribute to AF relapse. In this article, we summarise the rationale and current evidence supporting the arrhythmogenic role of non-PV triggers and our ablation approach to patients with non-paroxysmal AF.
AB - Pulmonary vein antrum isolation is the most effective rhythm control strategy in patients with paroxysmal AF. However, catheter ablation of non-paroxysmal AF has a lower success rate, even when persistent isolation of pulmonary veins (PVs) is achieved. As a result of arrhythmia-related electophysiological and structural changes in the atria, sites other than the PVs can harbour triggers. These non-PV triggers contribute to AF relapse. In this article, we summarise the rationale and current evidence supporting the arrhythmogenic role of non-PV triggers and our ablation approach to patients with non-paroxysmal AF.
KW - Atrial fibrillation
KW - Catheter ablation
KW - Non-pulmonary vein trigger
KW - Outcomes
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U2 - 10.15420/aer.2018.56.2
DO - 10.15420/aer.2018.56.2
M3 - Review article
AN - SCOPUS:85059617566
SN - 2050-3369
VL - 7
SP - 256
EP - 260
JO - Arrhythmia and Electrophysiology Review
JF - Arrhythmia and Electrophysiology Review
IS - 4
ER -