Peptide chain elongation: Discrimination against the initiator transfer RNA by microbial amino-acid polymerization factors

Yasushi Ono, Arthur Skoultchi, Albrecht Klein, Peter Lengyel

Research output: Contribution to journalArticle

60 Scopus citations

Abstract

The amino-acid polymerization factors S1 and S3 form complexes with most aminoacyl-tRNA species, including met-tRNAM, but not F-met-tRNAF and not met-tRNAF. This discrimination may be a basis for avoiding one kind of ambiguity in translation.

Original languageEnglish (US)
Pages (from-to)1304-1307
Number of pages4
JournalNature
Volume220
Issue number5174
DOIs
Publication statusPublished - Dec 1 1968
Externally publishedYes

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