Pediatric lead poisoning from folk prescription for treating epilepsy

Xiao lan Ying; Jian Xu; Morri Markowitz; Chong huai Yan

doi:10.1016/j.cca.2016.07.024

Pediatric lead poisoning from folk prescription for treating epilepsy

Xiao lan Ying, Jian Xu, Morri Markowitz, Chong huai Yan

Pediatrics

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Background A case of lead poisoning resulting from the ingestion of a folk remedy for treating epilepsy is reported. Results The initial blood lead concentration of this 6-y-old boy was 63.6 μg/dl upon admission. He presented with abdominal pain, constipation, and irritability. The patient's liver function tests were significantly increased. Through chelation therapy, the blood lead concentration dropped markedly and clinical symptoms greatly improved. His blood and urine samples were collected for the kinetic analysis of lead elimination. Conclusions Folk prescriptions for epilepsy should be considered as potential sources of lead intoxication. Lead poisoning should be taken into consideration for unknown causes of abdominal pain.

Original language	English (US)
Pages (from-to)	130-134
Number of pages	5
Journal	Clinica Chimica Acta
Volume	461
DOIs	https://doi.org/10.1016/j.cca.2016.07.024
State	Published - Oct 1 2016

Keywords

Chelation therapy
Children
Epilepsy
Folk remedy
Lead poisoning
Liver failure

ASJC Scopus subject areas

Biochemistry
Clinical Biochemistry
Biochemistry, medical

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10.1016/j.cca.2016.07.024

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title = "Pediatric lead poisoning from folk prescription for treating epilepsy",

abstract = "Background A case of lead poisoning resulting from the ingestion of a folk remedy for treating epilepsy is reported. Results The initial blood lead concentration of this 6-y-old boy was 63.6 μg/dl upon admission. He presented with abdominal pain, constipation, and irritability. The patient's liver function tests were significantly increased. Through chelation therapy, the blood lead concentration dropped markedly and clinical symptoms greatly improved. His blood and urine samples were collected for the kinetic analysis of lead elimination. Conclusions Folk prescriptions for epilepsy should be considered as potential sources of lead intoxication. Lead poisoning should be taken into consideration for unknown causes of abdominal pain.",

keywords = "Chelation therapy, Children, Epilepsy, Folk remedy, Lead poisoning, Liver failure",

author = "Ying, {Xiao lan} and Jian Xu and Morri Markowitz and Yan, {Chong huai}",

note = "Funding Information: This work was supported by the National Basic Research Program of China (973 Program) ( No. 2012CB525001 ). ",

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doi = "10.1016/j.cca.2016.07.024",

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TY - JOUR

T1 - Pediatric lead poisoning from folk prescription for treating epilepsy

AU - Ying, Xiao lan

AU - Xu, Jian

AU - Markowitz, Morri

AU - Yan, Chong huai

N1 - Funding Information: This work was supported by the National Basic Research Program of China (973 Program) ( No. 2012CB525001 ).

PY - 2016/10/1

Y1 - 2016/10/1

N2 - Background A case of lead poisoning resulting from the ingestion of a folk remedy for treating epilepsy is reported. Results The initial blood lead concentration of this 6-y-old boy was 63.6 μg/dl upon admission. He presented with abdominal pain, constipation, and irritability. The patient's liver function tests were significantly increased. Through chelation therapy, the blood lead concentration dropped markedly and clinical symptoms greatly improved. His blood and urine samples were collected for the kinetic analysis of lead elimination. Conclusions Folk prescriptions for epilepsy should be considered as potential sources of lead intoxication. Lead poisoning should be taken into consideration for unknown causes of abdominal pain.

AB - Background A case of lead poisoning resulting from the ingestion of a folk remedy for treating epilepsy is reported. Results The initial blood lead concentration of this 6-y-old boy was 63.6 μg/dl upon admission. He presented with abdominal pain, constipation, and irritability. The patient's liver function tests were significantly increased. Through chelation therapy, the blood lead concentration dropped markedly and clinical symptoms greatly improved. His blood and urine samples were collected for the kinetic analysis of lead elimination. Conclusions Folk prescriptions for epilepsy should be considered as potential sources of lead intoxication. Lead poisoning should be taken into consideration for unknown causes of abdominal pain.

KW - Chelation therapy

KW - Children

KW - Epilepsy

KW - Folk remedy

KW - Lead poisoning

KW - Liver failure

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Pediatric lead poisoning from folk prescription for treating epilepsy

Abstract

Keywords

ASJC Scopus subject areas

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