Pediatric cardiac surgery: Relevance to fetal and neonatal brain injury

Giles J. Peek, Susan R. Hintz

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Introduction In this chapter the impact of congenital heart disease and its surgical treatment on the neonatal brain will be discussed. Babies may have congenital cardiac disease as an isolated malformation or may have a heart defect as part of a larger spectrum of abnormalities, which may in turn be associated with a syndrome. In addition, these babies are often profoundly ill, presenting to medical attention on the verge of cardiac arrest with severe hypoxia, hypotension, or both. The treatment of the condition usually involves a trip to the catheterization laboratory or operating room (or both). We therefore have great potential for neurological morbidity, with a combination of possible underlying abnormality of the brain, preoperative, perioperative, and postoperative insults all conspiring to injure the cardiac surgery patient's brain. Despite these problems, the majority of babies do extremely well following heart surgery in the newborn period, although it is important to recognize that many of them will have a subtle neurological deficit if they are compared to the normal population. These are evidenced as cognitive and intellectual impairment, behavioral difficulties, speech delays, etc. The incidence of major neurological insult postoperatively as manifest by seizures, stroke, coma, or choreo-athetoid movements has fallen to around 2–11% in the current era.

Original languageEnglish (US)
Title of host publicationFetal and Neonatal Brain Injury, Fourth Edition
PublisherCambridge University Press
Pages443-452
Number of pages10
ISBN (Electronic)9780511581281
ISBN (Print)9780521888592
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

Fingerprint

Brain Injuries
Thoracic Surgery
Pediatrics
Heart Diseases
Brain
Athetosis
Language Development Disorders
Operating Rooms
Coma
Heart Arrest
Catheterization
Hypotension
Seizures
Stroke
Newborn Infant
Morbidity
Incidence
Therapeutics
Population
Cognitive Dysfunction

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Peek, G. J., & Hintz, S. R. (2009). Pediatric cardiac surgery: Relevance to fetal and neonatal brain injury. In Fetal and Neonatal Brain Injury, Fourth Edition (pp. 443-452). Cambridge University Press. https://doi.org/10.1017/CBO9780511581281.040

Pediatric cardiac surgery : Relevance to fetal and neonatal brain injury. / Peek, Giles J.; Hintz, Susan R.

Fetal and Neonatal Brain Injury, Fourth Edition. Cambridge University Press, 2009. p. 443-452.

Research output: Chapter in Book/Report/Conference proceedingChapter

Peek, GJ & Hintz, SR 2009, Pediatric cardiac surgery: Relevance to fetal and neonatal brain injury. in Fetal and Neonatal Brain Injury, Fourth Edition. Cambridge University Press, pp. 443-452. https://doi.org/10.1017/CBO9780511581281.040
Peek GJ, Hintz SR. Pediatric cardiac surgery: Relevance to fetal and neonatal brain injury. In Fetal and Neonatal Brain Injury, Fourth Edition. Cambridge University Press. 2009. p. 443-452 https://doi.org/10.1017/CBO9780511581281.040
Peek, Giles J. ; Hintz, Susan R. / Pediatric cardiac surgery : Relevance to fetal and neonatal brain injury. Fetal and Neonatal Brain Injury, Fourth Edition. Cambridge University Press, 2009. pp. 443-452
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