Pathophysiology of cholesterol gallstone disease

Piero Portincasa; Antonio Moschetta; Agostino Di Ciaula; Daniela Pontrelli; Rosa C. Sasso; Helen H. Wang; David Q.H. Wang

doi:10.1007/978-88-470-0763-5_3

Pathophysiology of cholesterol gallstone disease

Piero Portincasa, Antonio Moschetta, Agostino Di Ciaula, Daniela Pontrelli, Rosa C. Sasso, Helen H. Wang, David Q.H. Wang

Research output: Chapter in Book/Report/Conference proceeding › Chapter

10 Scopus citations

Abstract

Gallstone disease is one of the most costly digestive diseases requiring hospitalization in westernized countries, and its prevalence ranges from 10% to 15% in adults in Europe and the USA [1-4]. The burden of disease is summarized by the prevalence of patients with gallstones, by its incidence (over a million new diagnoses of gallstones a year), and by the number of cholecystectomies performed yearly in the USA (approaching 700,000) [5]. Similar trends in gallstone disease have been confirmed in large epidemiological surveys carried out in Italy [6-10]. In Western societies approximately 80% of gallstones are cholesterol gallstones [11], either pure cholesterol or mixed cholesterol stones (containing more than 50% cholesterol by weight).

Original language	English (US)
Title of host publication	Biliary Lithiasis
Subtitle of host publication	Basic Science, Current Diagnosis and Management
Publisher	Springer Milan
Pages	19-49
Number of pages	31
ISBN (Print)	9788847007628
DOIs	https://doi.org/10.1007/978-88-470-0763-5_3
State	Published - 2008
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1007/978-88-470-0763-5_3

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title = "Pathophysiology of cholesterol gallstone disease",

abstract = "Gallstone disease is one of the most costly digestive diseases requiring hospitalization in westernized countries, and its prevalence ranges from 10% to 15% in adults in Europe and the USA [1-4]. The burden of disease is summarized by the prevalence of patients with gallstones, by its incidence (over a million new diagnoses of gallstones a year), and by the number of cholecystectomies performed yearly in the USA (approaching 700,000) [5]. Similar trends in gallstone disease have been confirmed in large epidemiological surveys carried out in Italy [6-10]. In Western societies approximately 80% of gallstones are cholesterol gallstones [11], either pure cholesterol or mixed cholesterol stones (containing more than 50% cholesterol by weight).",

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AU - Portincasa, Piero

AU - Moschetta, Antonio

AU - Di Ciaula, Agostino

AU - Pontrelli, Daniela

AU - Sasso, Rosa C.

AU - Wang, Helen H.

AU - Wang, David Q.H.

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AB - Gallstone disease is one of the most costly digestive diseases requiring hospitalization in westernized countries, and its prevalence ranges from 10% to 15% in adults in Europe and the USA [1-4]. The burden of disease is summarized by the prevalence of patients with gallstones, by its incidence (over a million new diagnoses of gallstones a year), and by the number of cholecystectomies performed yearly in the USA (approaching 700,000) [5]. Similar trends in gallstone disease have been confirmed in large epidemiological surveys carried out in Italy [6-10]. In Western societies approximately 80% of gallstones are cholesterol gallstones [11], either pure cholesterol or mixed cholesterol stones (containing more than 50% cholesterol by weight).

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Pathophysiology of cholesterol gallstone disease

Abstract

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