Systemic lupus erythematosus (SLE) is characterized by a panoply of autoanti-bodies (more than 50). Some of them are more prevalent (anti-ds DNA > 80%) while others are less frequently detected, but highly specific for SLE (anti-Sm, 20%). In this review we will discuss the clinical significance of anti-RNP, anti-Ro, anti-La and anti-phospholipid antibodies. We will also summarize the clinical and experimental evidence for the pathogenic role attributed to each one of these antibodies.
|Original language||English (US)|
|Number of pages||14|
|Journal||International Archives of Allergy and Immunology|
|State||Published - 1993|
- Rheumatoid factor
ASJC Scopus subject areas
- Immunology and Allergy