Pathobiology of Christianson syndrome: Linking disrupted endosomal-lysosomal function with intellectual disability and sensory impairments

Medicine & Life Sciences

• Mental Retardation, X-Linked, Syndromic, Christianson Type 100%
• Intellectual Disability 44%
• Nervous System 19%
• Spinal Cord Dorsal Horn 18%
• Spinal Cord 12%
• G(M2) Ganglioside 12%
• Glycosphingolipids 10%
• Sodium-Hydrogen Exchangers 10%
• Phenotype 9%
• Loss of Function Mutation 8%
• Neuropathology 8%
• Peripheral Nervous System 8%
• Ataxia 8%
• Gray Matter 8%
• Patient Safety 7%
• Atrophy 6%
• Epilepsy 6%
• Theoretical Models 6%
• Population 6%
• Hot Temperature 6%
• Quality of Life 5%
• Neurons 4%
• Pain 4%
• Brain 3%
• Child 3%

Social Sciences

• intellectual disability 47%
• deficit 26%
• epilepsy 19%
• system development 17%
• pain 15%
• brain 13%
• vulnerability 12%
• quality of life 12%
• disability 10%
• regulation 9%