Paracervical block efficacy in office hysteroscopic sterilization

A randomized controlled trial

Scott Chudnoff, Mark Einstein, Mark D. Levie

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Objective: To estimate the efficacy of paracervical block compared with saline for pain relief during office hysteroscopic sterilization. Methods: This study was a randomized, placebo-controlled study of women desiring hysteroscopic sterilization. A paracervical block of 1% lidocaine or normal saline was administered before office hysteroscopic sterilization. Patients and investigators were blinded to assignments. A pre hoc power analysis determined that 40 women would be required per arm to detect a difference of 0.9 cm on a visual analog scale. Pain was recorded on a visual analog scale at multiple procedure time points. Individualized standardized pain scores were constructed by weighted reporting of Objective and subjective sensation. Results: A total of 103 consecutive women were eligible, and 80 women were randomized, with 40 per group. Thirty-seven (93%) in each group had successful placement. The lidocaine group showed significantly lower pain scores for tenaculum placement (mean±standard deviation: 0.97±1.28 compared with 3.00±2.41, P<.001) traversing the external cervical os (1.46±1.71 compared with 3.77±2.68, P<.001) and internal os (1.79±2.11 compared with 4.10±2.77, P<.001). There was no significant observed difference with device placement in tubal ostium (3.15±2.69 compared with 3.74±2.73, P=.33). Multivariable linear regression analysis demonstrated a relationship of pain to procedural time (P=.047) and to group assignment (P<.01). CONCLUSION: Paracervical block with 1% lidocaine provides effective pain relief for cervical manipulations during office hysteroscopic sterilization, but does not reduce the pain associated with upper uterine/tubal manipulation when placing the devices.

Original languageEnglish (US)
Pages (from-to)26-34
Number of pages9
JournalObstetrics and Gynecology
Volume115
Issue number1
DOIs
StatePublished - Jan 2010

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Obstetrical Anesthesia
Randomized Controlled Trials
Pain
Lidocaine
Visual Analog Scale
Spinal Manipulation
Equipment and Supplies
Linear Models
Placebos
Regression Analysis
Research Personnel

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Paracervical block efficacy in office hysteroscopic sterilization : A randomized controlled trial. / Chudnoff, Scott; Einstein, Mark; Levie, Mark D.

In: Obstetrics and Gynecology, Vol. 115, No. 1, 01.2010, p. 26-34.

Research output: Contribution to journalArticle

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