TY - JOUR
T1 - Pallidal deep brain stimulation for dystonia
T2 - A case series. Clinical article
AU - Petrossian, Melita T.
AU - Paul, Lisa R.
AU - Multhaupt-Buell, Trisha J.
AU - Eckhardt, Christine
AU - Hayes, Michael T.
AU - Duhaime, Ann Christine
AU - Eskandar, Emad N.
AU - Sharma, Nutan
PY - 2013/12
Y1 - 2013/12
N2 - Object. Pallidal deep brain stimulation (DBS) is a treatment option for those with early-onset dystonia. However, there are limited data on long-term outcome and treatment complications. The authors report on the short- and long-term effects of pallidal DBS in a cohort of patients with early-onset dystonia. Methods. Fourteen consecutive pediatric patients with early-onset dystonia were systematically evaluated and treated. The duration of follow-up ranged from 16 to 84 months. Results. There were no immediate postoperative complications. At last follow-up, 12 of the 14 patients displayed a significant decline in the Burke-Fahn-Marsden Dystonia Rating Scale motor subscale score, with an average decrease of 62% ± 8.4%. The most common hardware complication was lead fracture (14.3%). Conclusions. These data provide further evidence that DBS is a safe and effective treatment for those with early-onset dystonia.
AB - Object. Pallidal deep brain stimulation (DBS) is a treatment option for those with early-onset dystonia. However, there are limited data on long-term outcome and treatment complications. The authors report on the short- and long-term effects of pallidal DBS in a cohort of patients with early-onset dystonia. Methods. Fourteen consecutive pediatric patients with early-onset dystonia were systematically evaluated and treated. The duration of follow-up ranged from 16 to 84 months. Results. There were no immediate postoperative complications. At last follow-up, 12 of the 14 patients displayed a significant decline in the Burke-Fahn-Marsden Dystonia Rating Scale motor subscale score, with an average decrease of 62% ± 8.4%. The most common hardware complication was lead fracture (14.3%). Conclusions. These data provide further evidence that DBS is a safe and effective treatment for those with early-onset dystonia.
KW - Deep brain stimulation
KW - Early-onset dystonia
KW - Functional neurosurgery
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U2 - 10.3171/2013.8.PEDS13134
DO - 10.3171/2013.8.PEDS13134
M3 - Article
C2 - 24093589
AN - SCOPUS:84889254237
SN - 1933-0707
VL - 12
SP - 582
EP - 587
JO - Journal of Neurosurgery: Pediatrics
JF - Journal of Neurosurgery: Pediatrics
IS - 6
ER -