Pallidal deep brain stimulation for dystonia: A case series. Clinical article

Melita T. Petrossian, Lisa R. Paul, Trisha J. Multhaupt-Buell, Christine Eckhardt, Michael T. Hayes, Ann Christine Duhaime, Emad N. Eskandar, Nutan Sharma

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Object. Pallidal deep brain stimulation (DBS) is a treatment option for those with early-onset dystonia. However, there are limited data on long-term outcome and treatment complications. The authors report on the short- and long-term effects of pallidal DBS in a cohort of patients with early-onset dystonia. Methods. Fourteen consecutive pediatric patients with early-onset dystonia were systematically evaluated and treated. The duration of follow-up ranged from 16 to 84 months. Results. There were no immediate postoperative complications. At last follow-up, 12 of the 14 patients displayed a significant decline in the Burke-Fahn-Marsden Dystonia Rating Scale motor subscale score, with an average decrease of 62% ± 8.4%. The most common hardware complication was lead fracture (14.3%). Conclusions. These data provide further evidence that DBS is a safe and effective treatment for those with early-onset dystonia.

Original languageEnglish (US)
Pages (from-to)582-587
Number of pages6
JournalJournal of Neurosurgery: Pediatrics
Volume12
Issue number6
DOIs
StatePublished - Dec 1 2013
Externally publishedYes

Keywords

  • Deep brain stimulation
  • Early-onset dystonia
  • Functional neurosurgery

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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