Palliative Care in the Management of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome in the Primary Care Setting

Linda R. Mitchell, Nidhi Y. Shah, Peter A. Selwyn

Research output: Contribution to journalReview article


Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) has metamorphosed in the past 40 years since the first cases were diagnosed. The advent of highly active antiretroviral treatment (HAART) transformed the disease trajectory for many patients with HIV/AIDS and transitioned the course from a terminal disease to a chronic disease model. This article reviews the epidemiology of HIV/AIDS, prognostic indicators, frailty, opportunistic infections, specific AIDS-defining malignancies and non–AIDS-defining malignancies, role of palliative care, advance care planning, and the role of HAART in patients dying of late-stage AIDS.

Original languageEnglish (US)
JournalPrimary Care - Clinics in Office Practice
Publication statusPublished - Jan 1 2019



  • Aging population
  • Malignancies
  • Palliative care

ASJC Scopus subject areas

  • Pharmacology (medical)

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