Ovarian development in 46,XY gonadal dysgenesis

Marcia H. Russell, Stephen S. Wachtel, Ben W. Davis, Linda T. Cahill, Erich Groos, Gary D. Niblack, Ian M. Burr

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


In human the XY ovary is degenerative, there being scant evidence of persistence of that organ beyond the perinatal period. Here we describe indications of functional ovarian tissue in a 17-year-old female with male karyotype, H-Y+ cellular phenotype, and some signs of the Turner syndrome. Her gonads were removed after the onset of secondary amenorrhea. Histological examination revealed a degenerative right ovary devoid of germ cells and follicles, and a left streak gonad. There was no trace of testicular development in either side.

Original languageEnglish (US)
Pages (from-to)196-199
Number of pages4
JournalHuman Genetics
Issue number2
StatePublished - Jun 1982
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)


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