Outflow reconstruction in right hepatic live donor liver transplantation

Milan Kinkhabwala, James V. Guarrera, Richard Leno, Robert S. Brown, Joan Prowda, Sandip Kapur, Jean C. Emond

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Background. Inconstant venous anatomy increases the risk of outflow complications in right hepatic live donor liver transplantation (RH-LDT), but no consensus has emerged guiding optimal reconstruction for venous outflow. Methods. We retrospectively analyzed surgical venous reconstruction using a flexible approach to anterior accessory veins in 48 RH-LDTs performed between April, 1998 and July, 2002. Results. Actuarial recipient graft and patient survival was 79% and 85%, respectively. Single hepatic venous anastomosis was performed in 74% of the patients. Twelve patients underwent reconstruction of 20 accessory veins, including 7 posterior segment veins and 13 anterior segment veins. Anterior vein reconstruction techniques included end-to-end anastomosis to the middle hepatic vein, interposition conduit, venoplasty, or a combination of techniques. Documented complications related to the venous anastomosis occurred in only 1 patient (2%), with no patient having a documented venous thrombosis of either the main RHV or a reconstructed accessory vein. There were no differences in outcome based on single versus multiple venous reconstruction. Anteromedial congestion was noted in 3 patients in the absence of anatomic venous anastomotic complication, but the clinical significance of this finding is unclear. Conclusions. Despite variations in segmental venous drainage and a propensity for anteromedial congestion in right hepatic grafts, RH-LDT can be performed without outflow obstruction with close attention to a wide RHV anastomosis. In addition, anterior accessory vein reconstruction can be reserved for grafts of marginal size or quality where early postoperative venous congestion may impair early graft function. Routine extended hepatectomy incorporating the MHV with the graft is unnecessary.

Original languageEnglish (US)
Pages (from-to)243-250
Number of pages8
JournalSurgery
Volume133
Issue number3
DOIs
StatePublished - Mar 1 2003
Externally publishedYes

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Liver Transplantation
Veins
Tissue Donors
Liver
Transplants
Hepatic Veins
Hyperemia
Hepatectomy
Graft Survival
Venous Thrombosis
Drainage
Anatomy

ASJC Scopus subject areas

  • Surgery

Cite this

Kinkhabwala, M., Guarrera, J. V., Leno, R., Brown, R. S., Prowda, J., Kapur, S., & Emond, J. C. (2003). Outflow reconstruction in right hepatic live donor liver transplantation. Surgery, 133(3), 243-250. https://doi.org/10.1067/msy.2003.18

Outflow reconstruction in right hepatic live donor liver transplantation. / Kinkhabwala, Milan; Guarrera, James V.; Leno, Richard; Brown, Robert S.; Prowda, Joan; Kapur, Sandip; Emond, Jean C.

In: Surgery, Vol. 133, No. 3, 01.03.2003, p. 243-250.

Research output: Contribution to journalArticle

Kinkhabwala, M, Guarrera, JV, Leno, R, Brown, RS, Prowda, J, Kapur, S & Emond, JC 2003, 'Outflow reconstruction in right hepatic live donor liver transplantation', Surgery, vol. 133, no. 3, pp. 243-250. https://doi.org/10.1067/msy.2003.18
Kinkhabwala M, Guarrera JV, Leno R, Brown RS, Prowda J, Kapur S et al. Outflow reconstruction in right hepatic live donor liver transplantation. Surgery. 2003 Mar 1;133(3):243-250. https://doi.org/10.1067/msy.2003.18
Kinkhabwala, Milan ; Guarrera, James V. ; Leno, Richard ; Brown, Robert S. ; Prowda, Joan ; Kapur, Sandip ; Emond, Jean C. / Outflow reconstruction in right hepatic live donor liver transplantation. In: Surgery. 2003 ; Vol. 133, No. 3. pp. 243-250.
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