Outcome of dialysis in children with human immunodeficiency virus infection

Roberto Gordillo, Juhi Kumar, Marcela Del Rio, Joseph T. Flynn, Robert P. Woroniecki

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Human immunodeficiency virus (HIV) infection accounts for an unknown percentage of children with end-stage kidney disease (ESKD). Our objective was to compare the outcome of renal replacement therapy (RRT) in subjects with ESKD due to HIV and other diagnoses and to examine the prevalence of ESKD due to HIV. We analyzed Kt/V, morbidity, mortality, echocardiography, nutritional, and transplant status in 12 dialysis patients with HIV and 32 without HIV followed at our center between February 2002 and February 2007. Body mass index (BMI) was lower and Kt/V higher in HIV than in non-HIV patients. Shortening fraction was significantly lower in HIV patients. There were six deaths in the HIV group and one in the non-HIV group over the study period. Hemodialysis (HD) is the prevalent mode of RRT in HIV in urban settings, and its adequacy as measured by Kt/V was higher in HIV patients than in non-HIV patients. Decreased BMI and cardiovascular disease may be associated with increased mortality in children with HIV on RRT.

Original languageEnglish (US)
Pages (from-to)171-175
Number of pages5
JournalPediatric Nephrology
Volume24
Issue number1
DOIs
StatePublished - 2009

Fingerprint

Virus Diseases
Dialysis
HIV
Renal Replacement Therapy
Chronic Kidney Failure
Viruses
Body Mass Index
Child Mortality
Nutritional Status
Echocardiography
Renal Dialysis
Cardiovascular Diseases
Morbidity
Transplants

Keywords

  • Kt/V
  • Morbidity
  • Prevalence and mortality in HIV
  • Transplantation in HIV

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Cite this

Outcome of dialysis in children with human immunodeficiency virus infection. / Gordillo, Roberto; Kumar, Juhi; Del Rio, Marcela; Flynn, Joseph T.; Woroniecki, Robert P.

In: Pediatric Nephrology, Vol. 24, No. 1, 2009, p. 171-175.

Research output: Contribution to journalArticle

Gordillo, Roberto ; Kumar, Juhi ; Del Rio, Marcela ; Flynn, Joseph T. ; Woroniecki, Robert P. / Outcome of dialysis in children with human immunodeficiency virus infection. In: Pediatric Nephrology. 2009 ; Vol. 24, No. 1. pp. 171-175.
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