Orbital T-cell lymphoma in human T-cell leukemia virus-I infection

S. A. Lauer, J. Fischer, J. Jones, S. Gartner, J. Dutcher, J. A. Hoxie

Research output: Contribution to journalArticle

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Abstract

This is the first report of orbital involvement in systemic adult T-cell leukemia/lymphoma (ATLL). The etiologic agent of ATLL is the human T-cell leukemia virus-I (HTLV-I), the first retrovirus demonstrated to induce cancer in humans. The diagnosis of ATLL is based on characteristic clinicopathologic features in combination with serologic or virological evidence of HTLV-I infection. Serum antibodies to HTLV-I were identified by immunofluorescent microscopy. Viral particles characteristic of HTLV-I were found in a culture of the patient's peripheral blood lymphocytes. The patient was a native of the Caribbean, one of the known endemic foci of HTLV-I infection. Adult T-cell leukemia/lymphoma should be considered in the differential diagnosis of orbital T-cell lymphomas.

Original languageEnglish (US)
Pages (from-to)110-115
Number of pages6
JournalOphthalmology
Volume95
Issue number1
StatePublished - 1988

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Adult T Cell Leukemia Lymphoma
Human T-lymphotropic virus 1
T-Cell Lymphoma
Virus Diseases
HTLV-I Antibodies
Retroviridae
Virion
Microscopy
Differential Diagnosis
Lymphocytes
Serum
Neoplasms

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Lauer, S. A., Fischer, J., Jones, J., Gartner, S., Dutcher, J., & Hoxie, J. A. (1988). Orbital T-cell lymphoma in human T-cell leukemia virus-I infection. Ophthalmology, 95(1), 110-115.

Orbital T-cell lymphoma in human T-cell leukemia virus-I infection. / Lauer, S. A.; Fischer, J.; Jones, J.; Gartner, S.; Dutcher, J.; Hoxie, J. A.

In: Ophthalmology, Vol. 95, No. 1, 1988, p. 110-115.

Research output: Contribution to journalArticle

Lauer, SA, Fischer, J, Jones, J, Gartner, S, Dutcher, J & Hoxie, JA 1988, 'Orbital T-cell lymphoma in human T-cell leukemia virus-I infection', Ophthalmology, vol. 95, no. 1, pp. 110-115.
Lauer SA, Fischer J, Jones J, Gartner S, Dutcher J, Hoxie JA. Orbital T-cell lymphoma in human T-cell leukemia virus-I infection. Ophthalmology. 1988;95(1):110-115.
Lauer, S. A. ; Fischer, J. ; Jones, J. ; Gartner, S. ; Dutcher, J. ; Hoxie, J. A. / Orbital T-cell lymphoma in human T-cell leukemia virus-I infection. In: Ophthalmology. 1988 ; Vol. 95, No. 1. pp. 110-115.
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