Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia

Ho Sik Hwang, Kyong Jin Cho, Gabriel Rand, Roy S. Chuck, Ji Won Kwon

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Background: In our study we describe a method that optimizes size of excision and autografting for primary pterygia along with the use of intraoperative MMC and fibrin glue. Our objective is to propose a simple, optimizedpterygium surgical technique with excellent aesthetic outcomes and low rates of recurrence and otheradverse events. Methods: Retrospective chart review of 78 consecutive patients with stage III primary pterygia who underwent an optimal excision technique by three experienced surgeons. The technique consisted of removal of the pterygium head, excision of the pterygium body and Tenon's layer limited in proportion to the length of the head, application of intraoperative mitomycin C to the defect, harvest of superior bulbar limbal conjunctival graft, adherence of graft with fibrin glue. Outcomes included operative time, follow up period, pterygium recurrence, occurrences of incorrectly sized grafts, and other complications. Results: All patients were followed up for more than a year. Of the 78 patients, there were 2 cases of pterygium recurrence (2.6%). There was one case of wound dehiscence secondary to small-sized donor conjunctivaand one case of over-sized donor conjunctiva, neither of which required surgical correction. There were no toxic complications associated with the use of mitomycin C. Conclusion: Correlating the excision of the pterygium body and underlying Tenon's layer to the length of the pterygium head, along with the use intraoperative mitomycin C, limbal conjunctival autografting, and fibrin adhesionresulted in excellent outcomes with a low rate of recurrence for primary pterygia.

Original languageEnglish (US)
Article number135
JournalBMC Ophthalmology
Issue number1
StatePublished - Jun 7 2018
Externally publishedYes


  • Conjunctival autograft
  • Excision size
  • Fibrin adhesion
  • Mitomycin C
  • Primary pterygium

ASJC Scopus subject areas

  • Ophthalmology


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