Optical Coherence Tomography Imaging of Presumed Sarcoid Retinal and Optic Nerve Nodules

Naomi R. Goldberg, Douglas A. Jabs, Jacqueline Busingye

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Abstract: Purpose: To characterize nodular lesions of the retina and optic nerve with spectral-domain optical coherence tomography (SD-OCT) in patients with sarcoidosis. Methods: This is a retrospective series of 6 eyes from 5 patients with an established diagnosis of sarcoidosis, with clinically detected nodules of the optic nerve or retina. All lesions were imaged with fundus photography and SD-OCT on presentation, and followed with serial imaging after treatment with corticosteroids and/or immunomodulatory therapy. Results: Spectral OCT through the lesions revealed nodular hyperreflective processes obscuring the retinal layers or optic cup, with local structural changes, including subretinal and intraretinal fluid. After treatment with corticosteroids and/or immunosuppression in 4 followed patients, all lesions regressed with improvement in associated structural changes, but did not entirely disappear. Conclusions: Spectral OCT can be useful in identifying lesion morphology and location, and in tracking the response to treatment in eyes with posterior-segment nodules, presumably secondary to sarcoidosis.

Original languageEnglish (US)
Pages (from-to)293-296
Number of pages4
JournalOcular Immunology and Inflammation
Volume24
Issue number3
DOIs
StatePublished - May 3 2016
Externally publishedYes

Fingerprint

Optical Coherence Tomography
Sarcoidosis
Optic Nerve
Retina
Adrenal Cortex Hormones
Posterior Eye Segment
Subretinal Fluid
Immunomodulation
Photography
Immunosuppression
Therapeutics

Keywords

  • Granuloma
  • nodule
  • OCT
  • optic nerve
  • retina
  • sarcoidosis

ASJC Scopus subject areas

  • Ophthalmology
  • Immunology and Allergy

Cite this

Optical Coherence Tomography Imaging of Presumed Sarcoid Retinal and Optic Nerve Nodules. / Goldberg, Naomi R.; Jabs, Douglas A.; Busingye, Jacqueline.

In: Ocular Immunology and Inflammation, Vol. 24, No. 3, 03.05.2016, p. 293-296.

Research output: Contribution to journalArticle

Goldberg, Naomi R. ; Jabs, Douglas A. ; Busingye, Jacqueline. / Optical Coherence Tomography Imaging of Presumed Sarcoid Retinal and Optic Nerve Nodules. In: Ocular Immunology and Inflammation. 2016 ; Vol. 24, No. 3. pp. 293-296.
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