Ophthalmologic manifestations of Alzheimer's disease

Barrett Katz, Steve Rimmer

Research output: Contribution to journalReview article

131 Scopus citations

Abstract

Alzheimer's disease is a progressive neurologic disorder which may present with visual disturbance before the diagnosis is clearly established. Central acuity and visual field are initially normal. Alzheimer patients may show anomalies of color vision, spatial contrast sensitivity, susceptibility to visual masks, fundus examination, ocular motility, higher cortical visual function, visual evoked potential, and pattern electroretinogram. Pathologic analysis has shown abnormalities at all levels of the visual axis from retinal ganglion cell to associative visual cortex. Correlations between the visual abnormalities of Alzheimer's disease and corresponding neuroanatomic substrates are discussed.

Original languageEnglish (US)
Pages (from-to)31-43
Number of pages13
JournalSurvey of Ophthalmology
Volume34
Issue number1
DOIs
StatePublished - Jan 1 1989

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Keywords

  • Alzheimer's disease
  • aging
  • dementia
  • ocular manifestations of Alzheimer's disease

ASJC Scopus subject areas

  • Ophthalmology

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