Open Abdomen Management With Human Acellular Dermal Matrix in Liver Transplant Recipients

M. K. Singh, Juan P. Rocca, C. Rochon, M. E. Facciuto, P. A. Sheiner, M. I. Rodriguez-Davalos

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Background: Abdominal wall closure after liver transplantation is not always feasible and may result in increased intra-abdominal pressure along with associated complications. Various temporary closure techniques as well as open wound management have been used to address this complex problem. The aim of this series was to describe an approach to definitive wound closure of the open abdomen in liver transplant patients. Methods: We performed a retrospective review of all liver transplant patients at our institution from September 2005 to November 2007. The management of the open abdomen in 10 liver transplant patients was reviewed, and a novel approach described to manage these defects. Results: Ten patients with open wounds were closed during the study period using human acellular dermal matrix (HADM). There were 7 men and 3 women of median age 55 years. Average size of HADM was 235 cm2. The median follow-up is 10 months with no incidence of evisceration or hernia. In 1 patient, the graft failed along the lateral side due to infection; it dislodged during vacuum-assisted closure dressing change in another patient at 5 months after closure. Fascial closure was not possible due to organ edema (n = 3), a large liver (n = 4) or wound infection with dehiscence (n = 3). Conclusions: HADM can be used for primary wound closure in both clean and contaminated wounds as an alternative to an open abdomen post-liver transplantation.

Original languageEnglish (US)
Pages (from-to)3541-3544
Number of pages4
JournalTransplantation Proceedings
Volume40
Issue number10
DOIs
StatePublished - Dec 2008
Externally publishedYes

Fingerprint

Acellular Dermis
Abdomen
Liver
Wounds and Injuries
Transplants
Liver Transplantation
Negative-Pressure Wound Therapy
Abdominal Wall
Wound Infection
Bandages
Hernia
Transplant Recipients
Edema
Pressure
Incidence
Infection

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Open Abdomen Management With Human Acellular Dermal Matrix in Liver Transplant Recipients. / Singh, M. K.; Rocca, Juan P.; Rochon, C.; Facciuto, M. E.; Sheiner, P. A.; Rodriguez-Davalos, M. I.

In: Transplantation Proceedings, Vol. 40, No. 10, 12.2008, p. 3541-3544.

Research output: Contribution to journalArticle

Singh, M. K. ; Rocca, Juan P. ; Rochon, C. ; Facciuto, M. E. ; Sheiner, P. A. ; Rodriguez-Davalos, M. I. / Open Abdomen Management With Human Acellular Dermal Matrix in Liver Transplant Recipients. In: Transplantation Proceedings. 2008 ; Vol. 40, No. 10. pp. 3541-3544.
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