Ontology driven integration platform for clinical and translational research.

Parsa Mirhaji, Min Zhu, Mattew Vagnoni, Elmer V. Bernstam, Jiajie Zhang, Jack W. Smith

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Semantic Web technologies offer a promising framework for integration of disparate biomedical data. In this paper we present the semantic information integration platform under development at the Center for Clinical and Translational Sciences (CCTS) at the University of Texas Health Science Center at Houston (UTHSC-H) as part of our Clinical and Translational Science Award (CTSA) program. We utilize the Semantic Web technologies not only for integrating, repurposing and classification of multi-source clinical data, but also to construct a distributed environment for information sharing, and collaboration online. Service Oriented Architecture (SOA) is used to modularize and distribute reusable services in a dynamic and distributed environment. Components of the semantic solution and its overall architecture are described.

Original languageEnglish (US)
JournalBMC Bioinformatics
Volume10 Suppl 2
StatePublished - 2009
Externally publishedYes

Fingerprint

Translational Medical Research
Distributed Environment
Semantic Web
Semantics
Ontology
Information Integration
Information Sharing
Service-oriented Architecture
Service oriented architecture (SOA)
Dynamic Environment
Health
Technology
Information Dissemination
Information Storage and Retrieval
Collaboration
Framework
Architecture

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Computer Science Applications

Cite this

Mirhaji, P., Zhu, M., Vagnoni, M., Bernstam, E. V., Zhang, J., & Smith, J. W. (2009). Ontology driven integration platform for clinical and translational research. BMC Bioinformatics, 10 Suppl 2.

Ontology driven integration platform for clinical and translational research. / Mirhaji, Parsa; Zhu, Min; Vagnoni, Mattew; Bernstam, Elmer V.; Zhang, Jiajie; Smith, Jack W.

In: BMC Bioinformatics, Vol. 10 Suppl 2, 2009.

Research output: Contribution to journalArticle

Mirhaji, P, Zhu, M, Vagnoni, M, Bernstam, EV, Zhang, J & Smith, JW 2009, 'Ontology driven integration platform for clinical and translational research.', BMC Bioinformatics, vol. 10 Suppl 2.
Mirhaji P, Zhu M, Vagnoni M, Bernstam EV, Zhang J, Smith JW. Ontology driven integration platform for clinical and translational research. BMC Bioinformatics. 2009;10 Suppl 2.
Mirhaji, Parsa ; Zhu, Min ; Vagnoni, Mattew ; Bernstam, Elmer V. ; Zhang, Jiajie ; Smith, Jack W. / Ontology driven integration platform for clinical and translational research. In: BMC Bioinformatics. 2009 ; Vol. 10 Suppl 2.
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