Abstract
Protein S-nitrosation is an important post-translational modification. However, the detection of S-nitrosation is still problematic because S-nitrosation products, that is, S-nitrosothiols, are unstable species. Here a new reaction which can selectively convert unstable S-nitrosothiols to stable thioethers in one-pot under very mild conditions is reported. This reaction has the potential to be applied in the detection of protein S-nitrosation.
Original language | English (US) |
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Pages (from-to) | 5674-5676 |
Number of pages | 3 |
Journal | Organic Letters |
Volume | 12 |
Issue number | 24 |
DOIs | |
State | Published - Dec 17 2010 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry