One-pot thioether formation from S -nitrosothiols

Dehui Zhang, Nelmi O. Devarie-Baez, Jia Pan, Hua Wang, Ming Xian

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Protein S-nitrosation is an important post-translational modification. However, the detection of S-nitrosation is still problematic because S-nitrosation products, that is, S-nitrosothiols, are unstable species. Here a new reaction which can selectively convert unstable S-nitrosothiols to stable thioethers in one-pot under very mild conditions is reported. This reaction has the potential to be applied in the detection of protein S-nitrosation.

Original languageEnglish (US)
Pages (from-to)5674-5676
Number of pages3
JournalOrganic Letters
Volume12
Issue number24
DOIs
StatePublished - Dec 17 2010
Externally publishedYes

Fingerprint

S-Nitrosothiols
Nitrosation
Sulfides
proteins
Protein S
Post Translational Protein Processing
products

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Zhang, D., Devarie-Baez, N. O., Pan, J., Wang, H., & Xian, M. (2010). One-pot thioether formation from S -nitrosothiols. Organic Letters, 12(24), 5674-5676. https://doi.org/10.1021/ol102491n

One-pot thioether formation from S -nitrosothiols. / Zhang, Dehui; Devarie-Baez, Nelmi O.; Pan, Jia; Wang, Hua; Xian, Ming.

In: Organic Letters, Vol. 12, No. 24, 17.12.2010, p. 5674-5676.

Research output: Contribution to journalArticle

Zhang, D, Devarie-Baez, NO, Pan, J, Wang, H & Xian, M 2010, 'One-pot thioether formation from S -nitrosothiols', Organic Letters, vol. 12, no. 24, pp. 5674-5676. https://doi.org/10.1021/ol102491n
Zhang D, Devarie-Baez NO, Pan J, Wang H, Xian M. One-pot thioether formation from S -nitrosothiols. Organic Letters. 2010 Dec 17;12(24):5674-5676. https://doi.org/10.1021/ol102491n
Zhang, Dehui ; Devarie-Baez, Nelmi O. ; Pan, Jia ; Wang, Hua ; Xian, Ming. / One-pot thioether formation from S -nitrosothiols. In: Organic Letters. 2010 ; Vol. 12, No. 24. pp. 5674-5676.
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