Oncogenomics/proteomics of head and neck cancers

Jason I. Kass; Howard S. Moskowitz; Jennifer R. Grandis

doi:10.1007/978-3-319-27601-4_4

Oncogenomics/proteomics of head and neck cancers

Jason I. Kass, Howard S. Moskowitz, Jennifer R. Grandis

Otorhinolaryngology - Head & Neck Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Over the past 20 years, we have seen a rapid development in our understanding of the molecular mechanisms of head and neck squamous cell cancer (HNSCC). These discoveries are in large part the result of advances in technology. Here, we first review the major technologies in both oncogenomics and proteomics as they apply to HNSCC and then review the results of seminal studies. These data lay the foundation for the next decade of discovery in HNSCC and are relevant to the clinician and scientist.

Original language	English (US)
Title of host publication	Head and Neck Cancer
Subtitle of host publication	Multimodality Management, Second Edition
Publisher	Springer International Publishing
Pages	101-114
Number of pages	14
ISBN (Electronic)	9783319276014
ISBN (Print)	9783319275994
DOIs	https://doi.org/10.1007/978-3-319-27601-4_4
State	Published - Jan 1 2016

Keywords

Exome
Head and neck cancer
MALDI
Mass spectroscopy
Oncogene
Proteomics
RPPA
SELDI
Sequencing technology
The cancer genome atlas (TCGA)
Tissue microarray (TMA)

ASJC Scopus subject areas

Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/978-3-319-27601-4_4

Cite this

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abstract = "Over the past 20 years, we have seen a rapid development in our understanding of the molecular mechanisms of head and neck squamous cell cancer (HNSCC). These discoveries are in large part the result of advances in technology. Here, we first review the major technologies in both oncogenomics and proteomics as they apply to HNSCC and then review the results of seminal studies. These data lay the foundation for the next decade of discovery in HNSCC and are relevant to the clinician and scientist.",

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doi = "10.1007/978-3-319-27601-4_4",

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AU - Kass, Jason I.

AU - Moskowitz, Howard S.

AU - Grandis, Jennifer R.

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N2 - Over the past 20 years, we have seen a rapid development in our understanding of the molecular mechanisms of head and neck squamous cell cancer (HNSCC). These discoveries are in large part the result of advances in technology. Here, we first review the major technologies in both oncogenomics and proteomics as they apply to HNSCC and then review the results of seminal studies. These data lay the foundation for the next decade of discovery in HNSCC and are relevant to the clinician and scientist.

AB - Over the past 20 years, we have seen a rapid development in our understanding of the molecular mechanisms of head and neck squamous cell cancer (HNSCC). These discoveries are in large part the result of advances in technology. Here, we first review the major technologies in both oncogenomics and proteomics as they apply to HNSCC and then review the results of seminal studies. These data lay the foundation for the next decade of discovery in HNSCC and are relevant to the clinician and scientist.

KW - Exome

KW - Head and neck cancer

KW - MALDI

KW - Mass spectroscopy

KW - Oncogene

KW - Proteomics

KW - RPPA

KW - SELDI

KW - Sequencing technology

KW - The cancer genome atlas (TCGA)

KW - Tissue microarray (TMA)

UR - http://www.scopus.com/inward/record.url?scp=85017059522&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85017059522&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-27601-4_4

DO - 10.1007/978-3-319-27601-4_4

M3 - Chapter

AN - SCOPUS:85017059522

SN - 9783319275994

SP - 101

EP - 114

BT - Head and Neck Cancer

PB - Springer International Publishing

ER -

Oncogenomics/proteomics of head and neck cancers

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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