Oncogenomics/proteomics of head and neck cancers

Jason I. Kass, Howard S. Moskowitz, Jennifer R. Grandis

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Over the past 20 years, we have seen a rapid development in our understanding of the molecular mechanisms of head and neck squamous cell cancer (HNSCC). These discoveries are in large part the result of advances in technology. Here, we first review the major technologies in both oncogenomics and proteomics as they apply to HNSCC and then review the results of seminal studies. These data lay the foundation for the next decade of discovery in HNSCC and are relevant to the clinician and scientist.

Original languageEnglish (US)
Title of host publicationHead and Neck Cancer
Subtitle of host publicationMultimodality Management, Second Edition
PublisherSpringer International Publishing
Pages101-114
Number of pages14
ISBN (Electronic)9783319276014
ISBN (Print)9783319275994
DOIs
StatePublished - Jan 1 2016

Keywords

  • Exome
  • Head and neck cancer
  • MALDI
  • Mass spectroscopy
  • Oncogene
  • Proteomics
  • RPPA
  • SELDI
  • Sequencing technology
  • The cancer genome atlas (TCGA)
  • Tissue microarray (TMA)

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Kass, J. I., Moskowitz, H. S., & Grandis, J. R. (2016). Oncogenomics/proteomics of head and neck cancers. In Head and Neck Cancer: Multimodality Management, Second Edition (pp. 101-114). Springer International Publishing. https://doi.org/10.1007/978-3-319-27601-4_4