Omega-3 polyunsaturated fatty acid supplementation reduced atrial fibrillation recurrence after pulmonary vein antrum isolation

Dimpi Patel; Mazen Shaheen; Preeti Venkatraman; Luciana Armaganijan; Javier E. Sanchez; Rodney P. Horton; Luigi Di Biase; Prasant Mohanty; Robert Canby; Shane M. Bailey; J. David Burkhardt; G. Joesph Gallinghouse; Jason D. Zagrodzky; Marketa Kozeluhova; Andrea Natale

Omega-3 polyunsaturated fatty acid supplementation reduced atrial fibrillation recurrence after pulmonary vein antrum isolation

Dimpi Patel, Mazen Shaheen, Preeti Venkatraman, Luciana Armaganijan, Javier E. Sanchez, Rodney P. Horton, Luigi Di Biase, Prasant Mohanty, Robert Canby, Shane M. Bailey, J. David Burkhardt, G. Joesph Gallinghouse, Jason D. Zagrodzky, Marketa Kozeluhova, Andrea Natale

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Objective: To assess if patients treated with omega-3(n-3) polyunsaturated fatty acids (PUFAS) had lower procedural failure rates compared to an untreated population. Methods and Results: From January 2004 to 2007, 1500 PVAI patients underwent catheter ablation. Two hundred and eighty five (19%) patients were treated with PUFAs. These patients were matched in a nested case controlled analysis. After matching, there were 129 patients in the PUFA group and 129 in the control group. Thirty-five (27.1%) patients in the study group had early recurrence vs. 57 (44.1%) in the control group p-value<0.0001. Twenty-nine (23.2%) patients in the PUFA group vs. 41 (31.7%) in the non-PUFA group had procedural failure (p-value <0.003). There were no significant differences in complications in the PUFA and non-PUFA groups. Conclusion: Patients treated with PUFAs had lower incidences of early recurrence and procedural failure compared to an untreated population.

Original language	English (US)
Pages (from-to)	292-298
Number of pages	7
Journal	Indian Pacing and Electrophysiology Journal
Volume	9
Issue number	6
State	Published - 2009
Externally published	Yes

Keywords

Atrial Fibrillation (AF)
Polyunsaturated Fatty acids (PUFA)
Pulmonary vein isolation (PVAI)

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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Patel, D., Shaheen, M., Venkatraman, P., Armaganijan, L., Sanchez, J. E., Horton, R. P., Di Biase, L., Mohanty, P., Canby, R., Bailey, S. M., Burkhardt, J. D., Gallinghouse, G. J., Zagrodzky, J. D., Kozeluhova, M., & Natale, A. (2009). Omega-3 polyunsaturated fatty acid supplementation reduced atrial fibrillation recurrence after pulmonary vein antrum isolation. Indian Pacing and Electrophysiology Journal, 9(6), 292-298.

Patel, D, Shaheen, M, Venkatraman, P, Armaganijan, L, Sanchez, JE, Horton, RP, Di Biase, L, Mohanty, P, Canby, R, Bailey, SM, Burkhardt, JD, Gallinghouse, GJ, Zagrodzky, JD, Kozeluhova, M & Natale, A 2009, 'Omega-3 polyunsaturated fatty acid supplementation reduced atrial fibrillation recurrence after pulmonary vein antrum isolation', Indian Pacing and Electrophysiology Journal, vol. 9, no. 6, pp. 292-298.

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abstract = "Objective: To assess if patients treated with omega-3(n-3) polyunsaturated fatty acids (PUFAS) had lower procedural failure rates compared to an untreated population. Methods and Results: From January 2004 to 2007, 1500 PVAI patients underwent catheter ablation. Two hundred and eighty five (19%) patients were treated with PUFAs. These patients were matched in a nested case controlled analysis. After matching, there were 129 patients in the PUFA group and 129 in the control group. Thirty-five (27.1%) patients in the study group had early recurrence vs. 57 (44.1%) in the control group p-value<0.0001. Twenty-nine (23.2%) patients in the PUFA group vs. 41 (31.7%) in the non-PUFA group had procedural failure (p-value <0.003). There were no significant differences in complications in the PUFA and non-PUFA groups. Conclusion: Patients treated with PUFAs had lower incidences of early recurrence and procedural failure compared to an untreated population.",

keywords = "Atrial Fibrillation (AF), Polyunsaturated Fatty acids (PUFA), Pulmonary vein isolation (PVAI)",

author = "Dimpi Patel and Mazen Shaheen and Preeti Venkatraman and Luciana Armaganijan and Sanchez, {Javier E.} and Horton, {Rodney P.} and {Di Biase}, Luigi and Prasant Mohanty and Robert Canby and Bailey, {Shane M.} and Burkhardt, {J. David} and Gallinghouse, {G. Joesph} and Zagrodzky, {Jason D.} and Marketa Kozeluhova and Andrea Natale",

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T1 - Omega-3 polyunsaturated fatty acid supplementation reduced atrial fibrillation recurrence after pulmonary vein antrum isolation

AU - Patel, Dimpi

AU - Shaheen, Mazen

AU - Venkatraman, Preeti

AU - Armaganijan, Luciana

AU - Sanchez, Javier E.

AU - Horton, Rodney P.

AU - Di Biase, Luigi

AU - Mohanty, Prasant

AU - Canby, Robert

AU - Bailey, Shane M.

AU - Burkhardt, J. David

AU - Gallinghouse, G. Joesph

AU - Zagrodzky, Jason D.

AU - Kozeluhova, Marketa

AU - Natale, Andrea

PY - 2009

Y1 - 2009

N2 - Objective: To assess if patients treated with omega-3(n-3) polyunsaturated fatty acids (PUFAS) had lower procedural failure rates compared to an untreated population. Methods and Results: From January 2004 to 2007, 1500 PVAI patients underwent catheter ablation. Two hundred and eighty five (19%) patients were treated with PUFAs. These patients were matched in a nested case controlled analysis. After matching, there were 129 patients in the PUFA group and 129 in the control group. Thirty-five (27.1%) patients in the study group had early recurrence vs. 57 (44.1%) in the control group p-value<0.0001. Twenty-nine (23.2%) patients in the PUFA group vs. 41 (31.7%) in the non-PUFA group had procedural failure (p-value <0.003). There were no significant differences in complications in the PUFA and non-PUFA groups. Conclusion: Patients treated with PUFAs had lower incidences of early recurrence and procedural failure compared to an untreated population.

AB - Objective: To assess if patients treated with omega-3(n-3) polyunsaturated fatty acids (PUFAS) had lower procedural failure rates compared to an untreated population. Methods and Results: From January 2004 to 2007, 1500 PVAI patients underwent catheter ablation. Two hundred and eighty five (19%) patients were treated with PUFAs. These patients were matched in a nested case controlled analysis. After matching, there were 129 patients in the PUFA group and 129 in the control group. Thirty-five (27.1%) patients in the study group had early recurrence vs. 57 (44.1%) in the control group p-value<0.0001. Twenty-nine (23.2%) patients in the PUFA group vs. 41 (31.7%) in the non-PUFA group had procedural failure (p-value <0.003). There were no significant differences in complications in the PUFA and non-PUFA groups. Conclusion: Patients treated with PUFAs had lower incidences of early recurrence and procedural failure compared to an untreated population.

KW - Atrial Fibrillation (AF)

KW - Polyunsaturated Fatty acids (PUFA)

KW - Pulmonary vein isolation (PVAI)

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Omega-3 polyunsaturated fatty acid supplementation reduced atrial fibrillation recurrence after pulmonary vein antrum isolation

Abstract

Keywords

ASJC Scopus subject areas

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