Ollier disease with anaplastic astrocytoma: A review of the literature and a unique case

Srikanth Gajavelli, Jonathan Nakhla, Rani Nasser, Reza Yassari, Karen M. Weidenheim, Jerome Graber

Research output: Contribution to journalReview article

3 Scopus citations


Background: Ollier disease is a rare, nonfamilial disorder that primary affects the long bones and cartilage of joints with multiple enchondromas. It is associated with a higher risk of central nervous system (CNS) malignancies; although the incidence is unknown. Case Description: Here, we present the case of a 55-year-old woman who developed an anaplastic astrocytoma with a known diagnosis of Ollier disease with a survival time of over 3 years. Conclusion: This report draws attention to the rarity of this disease and the paucity of information regarding CNS involvement in Ollier disease, as well as reviews the current literature.

Original languageEnglish (US)
Pages (from-to)S607-S611
JournalSurgical Neurology International
Issue number24
StatePublished - Nov 1 2016



  • Astrocytoma
  • endochondroma
  • IDH1 mutation
  • intracranial tumor
  • Ollier Disease

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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