Olfactory function in dialysis patients

A potential key to understanding the uremic state

Andrew S. Bomback, Amanda C. Raff

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Impaired olfactory function is a marker of neurologic dysfunction in the uremic state. Retained uremic toxins not adequately cleared with dialysis may undermine the integrity of the olfactory epithelium and olfactory bulb and malign central olfactory processing. The evidence suggests that only renal transplantation, with its concomitant thorough reversal of uremia, truly restores olfactory function to normal in end-stage renal disease. Testing of olfactory function may emerge as an important marker for the extent and resolution of uremia.

Original languageEnglish (US)
Pages (from-to)803-805
Number of pages3
JournalKidney International
Volume80
Issue number8
DOIs
StatePublished - Oct 2 2011

Fingerprint

Uremia
Dialysis
Olfactory Mucosa
Olfactory Bulb
Neurologic Manifestations
Kidney Transplantation
Chronic Kidney Failure

ASJC Scopus subject areas

  • Nephrology

Cite this

Olfactory function in dialysis patients : A potential key to understanding the uremic state. / Bomback, Andrew S.; Raff, Amanda C.

In: Kidney International, Vol. 80, No. 8, 02.10.2011, p. 803-805.

Research output: Contribution to journalArticle

@article{4782da93ad574aa0933ce84293ffe211,
title = "Olfactory function in dialysis patients: A potential key to understanding the uremic state",
abstract = "Impaired olfactory function is a marker of neurologic dysfunction in the uremic state. Retained uremic toxins not adequately cleared with dialysis may undermine the integrity of the olfactory epithelium and olfactory bulb and malign central olfactory processing. The evidence suggests that only renal transplantation, with its concomitant thorough reversal of uremia, truly restores olfactory function to normal in end-stage renal disease. Testing of olfactory function may emerge as an important marker for the extent and resolution of uremia.",
author = "Bomback, {Andrew S.} and Raff, {Amanda C.}",
year = "2011",
month = "10",
day = "2",
doi = "10.1038/ki.2011.219",
language = "English (US)",
volume = "80",
pages = "803--805",
journal = "Kidney International",
issn = "0085-2538",
publisher = "Nature Publishing Group",
number = "8",

}

TY - JOUR

T1 - Olfactory function in dialysis patients

T2 - A potential key to understanding the uremic state

AU - Bomback, Andrew S.

AU - Raff, Amanda C.

PY - 2011/10/2

Y1 - 2011/10/2

N2 - Impaired olfactory function is a marker of neurologic dysfunction in the uremic state. Retained uremic toxins not adequately cleared with dialysis may undermine the integrity of the olfactory epithelium and olfactory bulb and malign central olfactory processing. The evidence suggests that only renal transplantation, with its concomitant thorough reversal of uremia, truly restores olfactory function to normal in end-stage renal disease. Testing of olfactory function may emerge as an important marker for the extent and resolution of uremia.

AB - Impaired olfactory function is a marker of neurologic dysfunction in the uremic state. Retained uremic toxins not adequately cleared with dialysis may undermine the integrity of the olfactory epithelium and olfactory bulb and malign central olfactory processing. The evidence suggests that only renal transplantation, with its concomitant thorough reversal of uremia, truly restores olfactory function to normal in end-stage renal disease. Testing of olfactory function may emerge as an important marker for the extent and resolution of uremia.

UR - http://www.scopus.com/inward/record.url?scp=80053511657&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80053511657&partnerID=8YFLogxK

U2 - 10.1038/ki.2011.219

DO - 10.1038/ki.2011.219

M3 - Article

VL - 80

SP - 803

EP - 805

JO - Kidney International

JF - Kidney International

SN - 0085-2538

IS - 8

ER -