Old microbes with new faces: molecular biology and the design of new vaccines

Nancy Connell, C. Kenneth Stover, William R. Jacobs

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Rational approaches to the design of live attenuated bacterial and viral recombinant vaccine strains are leading to the manipulation of old vaccines and the generation of new ones. The two basic problems to be solved are attenuation of pathogenic strains, and the stable expression of foreign.

Original languageEnglish (US)
Pages (from-to)442-448
Number of pages7
JournalCurrent Opinion in Immunology
Volume4
Issue number4
DOIs
StatePublished - 1992

Fingerprint

Viral Vaccines
Synthetic Vaccines
Molecular Biology
Vaccines

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Old microbes with new faces : molecular biology and the design of new vaccines. / Connell, Nancy; Stover, C. Kenneth; Jacobs, William R.

In: Current Opinion in Immunology, Vol. 4, No. 4, 1992, p. 442-448.

Research output: Contribution to journalArticle

@article{397daf74cb2d4d6ba2d76965a4a9c622,
title = "Old microbes with new faces: molecular biology and the design of new vaccines",
abstract = "Rational approaches to the design of live attenuated bacterial and viral recombinant vaccine strains are leading to the manipulation of old vaccines and the generation of new ones. The two basic problems to be solved are attenuation of pathogenic strains, and the stable expression of foreign.",
author = "Nancy Connell and Stover, {C. Kenneth} and Jacobs, {William R.}",
year = "1992",
doi = "10.1016/S0952-7915(06)80036-1",
language = "English (US)",
volume = "4",
pages = "442--448",
journal = "Current Opinion in Immunology",
issn = "0952-7915",
publisher = "Elsevier Limited",
number = "4",

}

TY - JOUR

T1 - Old microbes with new faces

T2 - molecular biology and the design of new vaccines

AU - Connell, Nancy

AU - Stover, C. Kenneth

AU - Jacobs, William R.

PY - 1992

Y1 - 1992

N2 - Rational approaches to the design of live attenuated bacterial and viral recombinant vaccine strains are leading to the manipulation of old vaccines and the generation of new ones. The two basic problems to be solved are attenuation of pathogenic strains, and the stable expression of foreign.

AB - Rational approaches to the design of live attenuated bacterial and viral recombinant vaccine strains are leading to the manipulation of old vaccines and the generation of new ones. The two basic problems to be solved are attenuation of pathogenic strains, and the stable expression of foreign.

UR - http://www.scopus.com/inward/record.url?scp=0026787679&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026787679&partnerID=8YFLogxK

U2 - 10.1016/S0952-7915(06)80036-1

DO - 10.1016/S0952-7915(06)80036-1

M3 - Article

C2 - 1388846

AN - SCOPUS:0026787679

VL - 4

SP - 442

EP - 448

JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

SN - 0952-7915

IS - 4

ER -