Old microbes with new faces: molecular biology and the design of new vaccines

Nancy Connell, C. Kenneth Stover, William R. Jacobs

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Rational approaches to the design of live attenuated bacterial and viral recombinant vaccine strains are leading to the manipulation of old vaccines and the generation of new ones. The two basic problems to be solved are attenuation of pathogenic strains, and the stable expression of foreign.

Original languageEnglish (US)
Pages (from-to)442-448
Number of pages7
JournalCurrent Opinion in Immunology
Volume4
Issue number4
DOIs
Publication statusPublished - 1992

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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