Obsessive-compulsive Disorder: Diagnostic and Treatment Issues

Dan J. Stein, Damiaan Denys, Andrew T. Gloster, Eric Hollander, James F. Leckman, Scott L. Rauch, Katharine A. Phillips

Research output: Contribution to journalReview article

24 Scopus citations


This article reviews current issues in the diagnosis and treatment of obsessive-compulsive disorder (OCD). The introduction of the selective serotonin reuptake inhibitors and of cognitive-behavioral therapy were significant advances for treating OCD. Nevertheless, there is a need to improve awareness of OCD and its management, and to develop novel approaches to treatment-refractory patients. Although the diagnostic criteria for OCD have remained unchanged for some time, there are several areas where potential modification may be useful. There is a growing evidence base on OCD symptom dimensions and subtyping, and it is timely to consider incorporating some of these emerging data into diagnostic classification systems.

Original languageEnglish (US)
Pages (from-to)665-685
Number of pages21
JournalPsychiatric Clinics of North America
Issue number3
StatePublished - Sep 1 2009


  • DSM-V
  • Diagnosis
  • Nosology
  • Obsessive-compulsive disorder
  • Obsessive-compulsive spectrum
  • Pharmacotherapy
  • Psychotherapy

ASJC Scopus subject areas

  • Psychiatry and Mental health

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    Stein, D. J., Denys, D., Gloster, A. T., Hollander, E., Leckman, J. F., Rauch, S. L., & Phillips, K. A. (2009). Obsessive-compulsive Disorder: Diagnostic and Treatment Issues. Psychiatric Clinics of North America, 32(3), 665-685. https://doi.org/10.1016/j.psc.2009.05.007