Objectively Measured Sedentary Behavior, Physical Activity, and Cardiometabolic Risk in Hispanic Youth: Hispanic Community Health Study/Study of Latino Youth

Garrett Strizich, Robert C. Kaplan, Daniela Sotres-Alvarez, Keith M. Diaz, Amber L. Daigre, Mercedes R. Carnethon, Denise C. Vidot, Alan M. Delamater, Lilian Perez, Krista Perreira, Carmen R. Isasi, Qibin Qi

Research output: Contribution to journalArticle

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Abstract

Context: Time spent in moderate-to-vigorous physical activity (MVPA), but not in sedentary behavior (SB), is related to cardiometabolic risk among non-Hispanic white youth. Objective: Examine associations of SB and MVPA with cardiometabolic risk factors among Hispanic/ Latino youth. Design: Cross-sectional analysis. Setting: Four US communities. Participants: Hispanic/Latino youth (N = 1,426) ages 8 to 16 years. Measurements: Associations of MVPA and SB, measured using 7-day accelerometer data (independent variables), with markers of glucose and lipid metabolism, inflammation, and endothelial function (dependent variables), were assessed in multivariable linear regression models while adjusting for sociodemographic characteristics and accelerometer wear time. Additional models controlled for obesity measures. Results: SB comprised a mean (SD) of 75% (13%) of accelerometer wear time; mean (SD) time of MVPA was 35 min/d (22 min/d). Deleterious levels of high-density lipoproteincholesterol (HDLC), triglycerides, insulin resistance, C-reactive protein, and plasminogen activator inhibitor-1 were associated with lower levels of MVPA and higher levels of SB (all P < 0.05). Associations of MVPA with log-transformed triglyceride concentrations (b per 15-min/d increment, 20.039; SE, 0.018; P = 0.037) and SB with HDL-C (b per 30-min/d increment, 20.63; SE, 0.26; P = 0.018), but not those with other markers, remained significant after adjusting for MVPA or SB and further adjustment for body mass index and waist circumference. Higher SB tertiles were associated with lower soluble receptor for advanced glycation end products in fully adjusted models (P for trend = 0.037). Conclusions: Physiological precursors of diabetes and cardiovascular disease were associated with MVPA and SB among US Hispanic/Latino youth, a group that bears a disproportionate burden of metabolic disorders.

Original languageEnglish (US)
Pages (from-to)3289-3298
Number of pages10
JournalJournal of Clinical Endocrinology and Metabolism
Volume103
Issue number9
DOIs
StatePublished - Sep 1 2018

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Accelerometers
Hispanic Americans
Health
Exercise
Triglycerides
Wear of materials
Plasminogen Activator Inhibitor 1
Medical problems
Linear regression
C-Reactive Protein
Insulin
Glucose
Linear Models
Waist Circumference
Lipid Metabolism
Insulin Resistance
Body Mass Index
Cardiovascular Diseases
Obesity
Cross-Sectional Studies

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

Objectively Measured Sedentary Behavior, Physical Activity, and Cardiometabolic Risk in Hispanic Youth : Hispanic Community Health Study/Study of Latino Youth. / Strizich, Garrett; Kaplan, Robert C.; Sotres-Alvarez, Daniela; Diaz, Keith M.; Daigre, Amber L.; Carnethon, Mercedes R.; Vidot, Denise C.; Delamater, Alan M.; Perez, Lilian; Perreira, Krista; Isasi, Carmen R.; Qi, Qibin.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 103, No. 9, 01.09.2018, p. 3289-3298.

Research output: Contribution to journalArticle

Strizich, Garrett ; Kaplan, Robert C. ; Sotres-Alvarez, Daniela ; Diaz, Keith M. ; Daigre, Amber L. ; Carnethon, Mercedes R. ; Vidot, Denise C. ; Delamater, Alan M. ; Perez, Lilian ; Perreira, Krista ; Isasi, Carmen R. ; Qi, Qibin. / Objectively Measured Sedentary Behavior, Physical Activity, and Cardiometabolic Risk in Hispanic Youth : Hispanic Community Health Study/Study of Latino Youth. In: Journal of Clinical Endocrinology and Metabolism. 2018 ; Vol. 103, No. 9. pp. 3289-3298.
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abstract = "Context: Time spent in moderate-to-vigorous physical activity (MVPA), but not in sedentary behavior (SB), is related to cardiometabolic risk among non-Hispanic white youth. Objective: Examine associations of SB and MVPA with cardiometabolic risk factors among Hispanic/ Latino youth. Design: Cross-sectional analysis. Setting: Four US communities. Participants: Hispanic/Latino youth (N = 1,426) ages 8 to 16 years. Measurements: Associations of MVPA and SB, measured using 7-day accelerometer data (independent variables), with markers of glucose and lipid metabolism, inflammation, and endothelial function (dependent variables), were assessed in multivariable linear regression models while adjusting for sociodemographic characteristics and accelerometer wear time. Additional models controlled for obesity measures. Results: SB comprised a mean (SD) of 75{\%} (13{\%}) of accelerometer wear time; mean (SD) time of MVPA was 35 min/d (22 min/d). Deleterious levels of high-density lipoproteincholesterol (HDLC), triglycerides, insulin resistance, C-reactive protein, and plasminogen activator inhibitor-1 were associated with lower levels of MVPA and higher levels of SB (all P < 0.05). Associations of MVPA with log-transformed triglyceride concentrations (b per 15-min/d increment, 20.039; SE, 0.018; P = 0.037) and SB with HDL-C (b per 30-min/d increment, 20.63; SE, 0.26; P = 0.018), but not those with other markers, remained significant after adjusting for MVPA or SB and further adjustment for body mass index and waist circumference. Higher SB tertiles were associated with lower soluble receptor for advanced glycation end products in fully adjusted models (P for trend = 0.037). Conclusions: Physiological precursors of diabetes and cardiovascular disease were associated with MVPA and SB among US Hispanic/Latino youth, a group that bears a disproportionate burden of metabolic disorders.",
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T1 - Objectively Measured Sedentary Behavior, Physical Activity, and Cardiometabolic Risk in Hispanic Youth

T2 - Hispanic Community Health Study/Study of Latino Youth

AU - Strizich, Garrett

AU - Kaplan, Robert C.

AU - Sotres-Alvarez, Daniela

AU - Diaz, Keith M.

AU - Daigre, Amber L.

AU - Carnethon, Mercedes R.

AU - Vidot, Denise C.

AU - Delamater, Alan M.

AU - Perez, Lilian

AU - Perreira, Krista

AU - Isasi, Carmen R.

AU - Qi, Qibin

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N2 - Context: Time spent in moderate-to-vigorous physical activity (MVPA), but not in sedentary behavior (SB), is related to cardiometabolic risk among non-Hispanic white youth. Objective: Examine associations of SB and MVPA with cardiometabolic risk factors among Hispanic/ Latino youth. Design: Cross-sectional analysis. Setting: Four US communities. Participants: Hispanic/Latino youth (N = 1,426) ages 8 to 16 years. Measurements: Associations of MVPA and SB, measured using 7-day accelerometer data (independent variables), with markers of glucose and lipid metabolism, inflammation, and endothelial function (dependent variables), were assessed in multivariable linear regression models while adjusting for sociodemographic characteristics and accelerometer wear time. Additional models controlled for obesity measures. Results: SB comprised a mean (SD) of 75% (13%) of accelerometer wear time; mean (SD) time of MVPA was 35 min/d (22 min/d). Deleterious levels of high-density lipoproteincholesterol (HDLC), triglycerides, insulin resistance, C-reactive protein, and plasminogen activator inhibitor-1 were associated with lower levels of MVPA and higher levels of SB (all P < 0.05). Associations of MVPA with log-transformed triglyceride concentrations (b per 15-min/d increment, 20.039; SE, 0.018; P = 0.037) and SB with HDL-C (b per 30-min/d increment, 20.63; SE, 0.26; P = 0.018), but not those with other markers, remained significant after adjusting for MVPA or SB and further adjustment for body mass index and waist circumference. Higher SB tertiles were associated with lower soluble receptor for advanced glycation end products in fully adjusted models (P for trend = 0.037). Conclusions: Physiological precursors of diabetes and cardiovascular disease were associated with MVPA and SB among US Hispanic/Latino youth, a group that bears a disproportionate burden of metabolic disorders.

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