Obesity and quality of life

Mediating effects of pain and comorbidities

Moonseong Heo, David B. Allison, Myles S. Faith, Shankuan Zhu, Kevin R. Fontaine

Research output: Contribution to journalArticle

150 Citations (Scopus)

Abstract

Objective: To estimate the association between body mass index (BMI) and health-related quality of life (HRQL) and examine whether joint pain and obesity-related comorbidities mediate the BMI-HRQL association. Research Methods and Procedures: Population-based survey data from the 1999 Behavioral Risk Factor Surveillance Survey. Adults (N = 155,989) were classified according to BMI as underweight (<18.5 kg/m2), desirable weight (18.5 to 24.9 kg/m2), overweight (25 to 29.9 kg/m2), obese class I (30 to 34.9 kg/m2), obese class II (35 to 39.9 kg/m2), and obese class III (≥40 kg/m2). Data including general health status, unhealthy days in the past 30 caused by physical problems and mental problems, and total unhealthy days in the past 30 were collected. Results: After adjusting for age, sex, race, smoking, education, and income, we observed J-shaped associations between BMI and HRQL. Compared with desirable weight adults, underweight, overweight, and obesity classes I, II, and III adults [odds ratio (OR) = 1.57, 1.19, 1.95, 2.72, and 4.36, respectively] were significantly (p < 0.001) more likely to report fair/poor general health status. For unhealthy days caused by physical problems, the corresponding ORs were 1.51, 1.15, 1.66, 2.27, and 3.61 (p < 0.001). For unhealthy days caused by mental problems, the ORs were 1.35, 1.14 1.43, 1.57, and 2.25 (p < 0.001). For total unhealthy days, the corresponding ORs were 1.27, 1.09, 1.37, 1.73, and 2.46 (p < 0.01). Adding joint pain and obesity-related comorbidities into models attenuated BMI-HRQL associations. Discussion: Associations between BMI and HRQL indices were J-shaped. Joint pain and comorbidities may mediate BMI-HRQL associations.

Original languageEnglish (US)
Pages (from-to)209-216
Number of pages8
JournalObesity Research
Volume11
Issue number2
StatePublished - 2003
Externally publishedYes

Fingerprint

quality of life
body mass index
Comorbidity
pain
Body Mass Index
obesity
Obesity
Quality of Life
Pain
Arthralgia
underweight
Thinness
health status
Health Status
Weights and Measures
research methods
comorbidity
odds ratio
education
income

Keywords

  • Comorbidities
  • Health-related quality of life
  • Joint pain
  • Mediators

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Public Health, Environmental and Occupational Health
  • Endocrinology
  • Food Science
  • Endocrinology, Diabetes and Metabolism

Cite this

Heo, M., Allison, D. B., Faith, M. S., Zhu, S., & Fontaine, K. R. (2003). Obesity and quality of life: Mediating effects of pain and comorbidities. Obesity Research, 11(2), 209-216.

Obesity and quality of life : Mediating effects of pain and comorbidities. / Heo, Moonseong; Allison, David B.; Faith, Myles S.; Zhu, Shankuan; Fontaine, Kevin R.

In: Obesity Research, Vol. 11, No. 2, 2003, p. 209-216.

Research output: Contribution to journalArticle

Heo, M, Allison, DB, Faith, MS, Zhu, S & Fontaine, KR 2003, 'Obesity and quality of life: Mediating effects of pain and comorbidities', Obesity Research, vol. 11, no. 2, pp. 209-216.
Heo M, Allison DB, Faith MS, Zhu S, Fontaine KR. Obesity and quality of life: Mediating effects of pain and comorbidities. Obesity Research. 2003;11(2):209-216.
Heo, Moonseong ; Allison, David B. ; Faith, Myles S. ; Zhu, Shankuan ; Fontaine, Kevin R. / Obesity and quality of life : Mediating effects of pain and comorbidities. In: Obesity Research. 2003 ; Vol. 11, No. 2. pp. 209-216.
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