Nucleated red blood cells in growth-restricted fetuses

Associations with short-term neonatal outcome

Victoria K. Minior, Peter S. Bernstein, Michael Y. Divon

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Objective: To determine the utility of the neonatal nucleated red blood cell (NRBC) count as an independent predictor of short-term perinatal outcome in growth-restricted fetuses. Methods: Hospital charts of neonates with a discharge diagnosis indicating a birth weight < 10th percentile were reviewed for perinatal outcome. We studied all eligible neonates who had a complete blood count on the first day of life. After multiple gestations, anomalous fetuses and diabetic pregnancies were excluded; 73 neonates comprised the study group. Statistical analysis included ANOVA, simple and stepwise regression. Results: Elevated NRBC counts were significantly associated with cesarean section for non-reassuring fetal status, neonatal intensive care unit admission and duration of neonatal intensive care unit stay, respiratory distress and intubation, thrombocytopenia, hyperbilirubinemia, intraventricular hemorrhage and neonatal death. Stepwise regression analysis including gestational age at birth, birth weight and NRBC count demonstrated that in growth-restricted fetuses, NRBC count was the strongest predictor of neonatal intraventricular hemorrhage, neonatal respiratory distress and neonatal death. Conclusion: An elevated NRBC count independently predicts adverse perinatal outcome in growth-restricted fetuses. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)165-169
Number of pages5
JournalFetal Diagnosis and Therapy
Volume15
Issue number3
StatePublished - May 2000

Fingerprint

Erythrocyte Count
Fetus
Erythrocytes
Growth
Neonatal Intensive Care Units
Birth Weight
Hemorrhage
Pregnancy
Hyperbilirubinemia
Blood Cell Count
Intubation
Cesarean Section
Thrombocytopenia
Gestational Age
Analysis of Variance
Regression Analysis
Parturition

Keywords

  • Fetal growth restriction
  • Nucleated red blood cells
  • Perinatal outcome

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Nucleated red blood cells in growth-restricted fetuses : Associations with short-term neonatal outcome. / Minior, Victoria K.; Bernstein, Peter S.; Divon, Michael Y.

In: Fetal Diagnosis and Therapy, Vol. 15, No. 3, 05.2000, p. 165-169.

Research output: Contribution to journalArticle

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