Abstract
Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 607-608 |
| Number of pages | 2 |
| Journal | Developmental cell |
| Volume | 4 |
| Issue number | 5 |
| DOIs |
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| State | Published - May 2003 |
ASJC Scopus subject areas
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Developmental Biology
- Cell Biology
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Cite this
Roy-Chowdhury, J., Locker, J., & Roy-Chowdhury, N. (2003). Nuclear receptors orchestrate detoxification pathways. Developmental cell, 4(5), 607-608. https://doi.org/10.1016/S1534-5807(03)00131-X