Nuclear receptors orchestrate detoxification pathways.

Jayanta Roy-Chowdhury, Joseph Locker, Namita Roy-Chowdhury

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.

Original languageEnglish (US)
Pages (from-to)607-608
Number of pages2
JournalDevelopmental Cell
Volume4
Issue number5
StatePublished - May 2003

Fingerprint

Detoxification
Xenobiotics
Cytoplasmic and Nuclear Receptors
Bilirubin
Enzymes
Pharmaceutical Preparations
Proteins

ASJC Scopus subject areas

  • Developmental Biology

Cite this

Roy-Chowdhury, J., Locker, J., & Roy-Chowdhury, N. (2003). Nuclear receptors orchestrate detoxification pathways. Developmental Cell, 4(5), 607-608.

Nuclear receptors orchestrate detoxification pathways. / Roy-Chowdhury, Jayanta; Locker, Joseph; Roy-Chowdhury, Namita.

In: Developmental Cell, Vol. 4, No. 5, 05.2003, p. 607-608.

Research output: Contribution to journalArticle

Roy-Chowdhury, J, Locker, J & Roy-Chowdhury, N 2003, 'Nuclear receptors orchestrate detoxification pathways.', Developmental Cell, vol. 4, no. 5, pp. 607-608.
Roy-Chowdhury, Jayanta ; Locker, Joseph ; Roy-Chowdhury, Namita. / Nuclear receptors orchestrate detoxification pathways. In: Developmental Cell. 2003 ; Vol. 4, No. 5. pp. 607-608.
@article{bef9240432774fc88540471d3ca59b58,
title = "Nuclear receptors orchestrate detoxification pathways.",
abstract = "Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.",
author = "Jayanta Roy-Chowdhury and Joseph Locker and Namita Roy-Chowdhury",
year = "2003",
month = "5",
language = "English (US)",
volume = "4",
pages = "607--608",
journal = "Developmental Cell",
issn = "1534-5807",
publisher = "Cell Press",
number = "5",

}

TY - JOUR

T1 - Nuclear receptors orchestrate detoxification pathways.

AU - Roy-Chowdhury, Jayanta

AU - Locker, Joseph

AU - Roy-Chowdhury, Namita

PY - 2003/5

Y1 - 2003/5

N2 - Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.

AB - Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.

UR - http://www.scopus.com/inward/record.url?scp=0037607405&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037607405&partnerID=8YFLogxK

M3 - Article

C2 - 12737794

AN - SCOPUS:0037607405

VL - 4

SP - 607

EP - 608

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 5

ER -