Abstract
Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 607-608 |
| Number of pages | 2 |
| Journal | Developmental Cell |
| Volume | 4 |
| Issue number | 5 |
| State | Published - May 2003 |
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ASJC Scopus subject areas
- Developmental Biology
Cite this
Nuclear receptors orchestrate detoxification pathways. / Roy-Chowdhury, Jayanta; Locker, Joseph; Roy-Chowdhury, Namita.
In: Developmental Cell, Vol. 4, No. 5, 05.2003, p. 607-608.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nuclear receptors orchestrate detoxification pathways.
AU - Roy-Chowdhury, Jayanta
AU - Locker, Joseph
AU - Roy-Chowdhury, Namita
PY - 2003/5
Y1 - 2003/5
N2 - Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.
AB - Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.
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UR - http://www.scopus.com/inward/citedby.url?scp=0037607405&partnerID=8YFLogxK
M3 - Article
C2 - 12737794
AN - SCOPUS:0037607405
VL - 4
SP - 607
EP - 608
JO - Developmental Cell
JF - Developmental Cell
SN - 1534-5807
IS - 5
ER -