Nuclear receptors orchestrate detoxification pathways.

Jayanta Roy-Chowdhury, Joseph Locker, Namita Roy-Chowdhury

Research output: Contribution to journalComment/debate

23 Scopus citations

Abstract

Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.

Original languageEnglish (US)
Pages (from-to)607-608
Number of pages2
JournalDevelopmental cell
Volume4
Issue number5
DOIs
StatePublished - May 2003

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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