Novel VIM metallo-β-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia

Maria Camila Montealegre, Adriana Correa, David F. Briceño, Natalia C. Rosas, Elsa De La Cadena, Sory J. Ruiz, Maria F. Mojica, Ruben Dario Camargo, Ivan Zuluaga, Adriana Marin, John P. Quinn, Maria Virginia Villegas, Henry Mendoza, Flor Angela Cubides, Martha Patricia Melendez, Luz Angelica Quintero, Ilba Liliana Galeano, Beatriz Porras, Guillermo Ortiz, Luz Mila LopezHenry Oliveros, Maria Nilse Gonzalez, Angela Pescador, Monica Ballesteros, Sandra Valderrama, Alirio Rodriguez, Jairo Perez, Carlos Ignacio Gomez, Jaime Lopez, Jorge Donado, Monica Cuartas, Ana Lucia Correa, Lina Marcela Castañeda, Julian Betancourth, Juan David Villa, Jorge Nagles, Nancy Estella Gonzalez, Magda Orjuela, Ana Cristina Quiroga, Rodrigo Agudelo, Carolina Rios, Martha Vallejo, Luz Marina Melguizo, Dora Rivas, Sergio Velez, Ernesto Martinez, Jose Millan Oñate, Christian Pallares, Luz Marina Gallardo, Alba Lucia Bohorques, Nancy Villamarin, Fernando Rosso, Juan Diego Velez, Jose Garcia, Monica Recalde, Alejandra Toala, John Jairo Echeverry, Beatriz Lopez, Claudia Barcenas, Karol Monsalve, Luis Angel Villar, Mayerly Anaya, Agustin Vega, Miriam Fanny Amaya, Matha Jacome, Rocio Abaunza, Martin Mejía, Angela Mendoza, Carmen Elisa Llano, Myriam Gomez, Rodolfo Cabrales, Amparo Ovalle, Claudia Echeverry, M. Del Rosario Aldana, Pablo Lopez, Luis Gonzalez

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

We report the emergence of a novel VIM variant (VIM-24) in a Klebsiella pneumoniae isolate in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints, posing a real challenge for its detection. The blaVIM-24 gene was located within a class 1 integron carried on a large plasmid. Further studies are needed to clarify its epidemiological and clinical impact.

Original languageEnglish (US)
Pages (from-to)2428-2430
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume55
Issue number5
DOIs
StatePublished - May 2011

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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