Novel translational research concepts and strategies in radiation oncology

Seema Gupta, P. K. Goyal, Mansoor M. Ahmed

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The discovery of X-rays by Roentgen in 1895 and the discovery of radiations emitted from Uranium compounds by Becquerel led to the establishment of the field of Radiation Sciences. When Radiation Sciences utilized the knowledge in the field of Physics, Chemistry, Biology and Medicine, newer fields were established such as Radiation -Oncology, -Chemistry, -Biology, -Protection, - Physics, Radiology and Nuclear Medicine. Fields of Radiation Oncology and Radiation Biology have gained significant strides by embracing the modern concepts in molecular biology and physics of imaging. To discuss the recent trends and advances in these fields, Indian Society for Radiation Biology organized an "International Conference on Radiation Biology and Translational Research in Radiation Oncology (ICRB-TRRO)" in Jaipur, India during November 10-12, 2008. The primary theme of this international meeting was to focus on the translational research perspectives in radiation oncology using radiation biology findings as a reservoir of ideas. The second major theme was to focus on research initiatives and recent perspectives in radiation protection. A common dynamic theme constantly interacted with the primary and secondary themes was an influx of extensive discussion on the scientific utility and validity of novel agents obtained from different traditional systems of Indian medicine and herbal plant extracts that can be potent radio-sensitizers as well as potent radio-protectors (as countermeasure agents). Overall, four major thrust areas of the conference such as Radiation-induced signaling networks, novel therapeutics for cancer, radiation-induced DNA damage-repair and novel imaging methods provided new insights and directions that had set roads to advancements in radiation biology.

Original languageEnglish (US)
Pages (from-to)103-111
Number of pages9
JournalMolecular and Cellular Pharmacology
Volume1
Issue number2
DOIs
StatePublished - 2009
Externally publishedYes

Fingerprint

Radiobiology
Radiation Oncology
Translational Medical Research
Physics
Radiation
Radio
Uranium Compounds
Radiation-Induced Neoplasms
Radiation Protection
Nuclear Medicine
Plant Extracts
Systems Analysis
Radiology
DNA Repair
DNA Damage
Molecular Biology
India
X-Rays
Medicine
Research

Keywords

  • Apoptosis
  • Bystander effects
  • DNA repair
  • Energy balance
  • Imaging
  • Low dose fractionated radiation therapy

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Molecular Biology

Cite this

Novel translational research concepts and strategies in radiation oncology. / Gupta, Seema; Goyal, P. K.; Ahmed, Mansoor M.

In: Molecular and Cellular Pharmacology, Vol. 1, No. 2, 2009, p. 103-111.

Research output: Contribution to journalArticle

Gupta, Seema ; Goyal, P. K. ; Ahmed, Mansoor M. / Novel translational research concepts and strategies in radiation oncology. In: Molecular and Cellular Pharmacology. 2009 ; Vol. 1, No. 2. pp. 103-111.
@article{503fad129db84326948a25d318d39263,
title = "Novel translational research concepts and strategies in radiation oncology",
abstract = "The discovery of X-rays by Roentgen in 1895 and the discovery of radiations emitted from Uranium compounds by Becquerel led to the establishment of the field of Radiation Sciences. When Radiation Sciences utilized the knowledge in the field of Physics, Chemistry, Biology and Medicine, newer fields were established such as Radiation -Oncology, -Chemistry, -Biology, -Protection, - Physics, Radiology and Nuclear Medicine. Fields of Radiation Oncology and Radiation Biology have gained significant strides by embracing the modern concepts in molecular biology and physics of imaging. To discuss the recent trends and advances in these fields, Indian Society for Radiation Biology organized an {"}International Conference on Radiation Biology and Translational Research in Radiation Oncology (ICRB-TRRO){"} in Jaipur, India during November 10-12, 2008. The primary theme of this international meeting was to focus on the translational research perspectives in radiation oncology using radiation biology findings as a reservoir of ideas. The second major theme was to focus on research initiatives and recent perspectives in radiation protection. A common dynamic theme constantly interacted with the primary and secondary themes was an influx of extensive discussion on the scientific utility and validity of novel agents obtained from different traditional systems of Indian medicine and herbal plant extracts that can be potent radio-sensitizers as well as potent radio-protectors (as countermeasure agents). Overall, four major thrust areas of the conference such as Radiation-induced signaling networks, novel therapeutics for cancer, radiation-induced DNA damage-repair and novel imaging methods provided new insights and directions that had set roads to advancements in radiation biology.",
keywords = "Apoptosis, Bystander effects, DNA repair, Energy balance, Imaging, Low dose fractionated radiation therapy",
author = "Seema Gupta and Goyal, {P. K.} and Ahmed, {Mansoor M.}",
year = "2009",
doi = "10.4255/mcpharmacol.09.13",
language = "English (US)",
volume = "1",
pages = "103--111",
journal = "Molecular and Cellular Pharmacology",
issn = "1938-1247",
publisher = "Lumitext Publishing",
number = "2",

}

TY - JOUR

T1 - Novel translational research concepts and strategies in radiation oncology

AU - Gupta, Seema

AU - Goyal, P. K.

AU - Ahmed, Mansoor M.

PY - 2009

Y1 - 2009

N2 - The discovery of X-rays by Roentgen in 1895 and the discovery of radiations emitted from Uranium compounds by Becquerel led to the establishment of the field of Radiation Sciences. When Radiation Sciences utilized the knowledge in the field of Physics, Chemistry, Biology and Medicine, newer fields were established such as Radiation -Oncology, -Chemistry, -Biology, -Protection, - Physics, Radiology and Nuclear Medicine. Fields of Radiation Oncology and Radiation Biology have gained significant strides by embracing the modern concepts in molecular biology and physics of imaging. To discuss the recent trends and advances in these fields, Indian Society for Radiation Biology organized an "International Conference on Radiation Biology and Translational Research in Radiation Oncology (ICRB-TRRO)" in Jaipur, India during November 10-12, 2008. The primary theme of this international meeting was to focus on the translational research perspectives in radiation oncology using radiation biology findings as a reservoir of ideas. The second major theme was to focus on research initiatives and recent perspectives in radiation protection. A common dynamic theme constantly interacted with the primary and secondary themes was an influx of extensive discussion on the scientific utility and validity of novel agents obtained from different traditional systems of Indian medicine and herbal plant extracts that can be potent radio-sensitizers as well as potent radio-protectors (as countermeasure agents). Overall, four major thrust areas of the conference such as Radiation-induced signaling networks, novel therapeutics for cancer, radiation-induced DNA damage-repair and novel imaging methods provided new insights and directions that had set roads to advancements in radiation biology.

AB - The discovery of X-rays by Roentgen in 1895 and the discovery of radiations emitted from Uranium compounds by Becquerel led to the establishment of the field of Radiation Sciences. When Radiation Sciences utilized the knowledge in the field of Physics, Chemistry, Biology and Medicine, newer fields were established such as Radiation -Oncology, -Chemistry, -Biology, -Protection, - Physics, Radiology and Nuclear Medicine. Fields of Radiation Oncology and Radiation Biology have gained significant strides by embracing the modern concepts in molecular biology and physics of imaging. To discuss the recent trends and advances in these fields, Indian Society for Radiation Biology organized an "International Conference on Radiation Biology and Translational Research in Radiation Oncology (ICRB-TRRO)" in Jaipur, India during November 10-12, 2008. The primary theme of this international meeting was to focus on the translational research perspectives in radiation oncology using radiation biology findings as a reservoir of ideas. The second major theme was to focus on research initiatives and recent perspectives in radiation protection. A common dynamic theme constantly interacted with the primary and secondary themes was an influx of extensive discussion on the scientific utility and validity of novel agents obtained from different traditional systems of Indian medicine and herbal plant extracts that can be potent radio-sensitizers as well as potent radio-protectors (as countermeasure agents). Overall, four major thrust areas of the conference such as Radiation-induced signaling networks, novel therapeutics for cancer, radiation-induced DNA damage-repair and novel imaging methods provided new insights and directions that had set roads to advancements in radiation biology.

KW - Apoptosis

KW - Bystander effects

KW - DNA repair

KW - Energy balance

KW - Imaging

KW - Low dose fractionated radiation therapy

UR - http://www.scopus.com/inward/record.url?scp=77953385017&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953385017&partnerID=8YFLogxK

U2 - 10.4255/mcpharmacol.09.13

DO - 10.4255/mcpharmacol.09.13

M3 - Article

AN - SCOPUS:77953385017

VL - 1

SP - 103

EP - 111

JO - Molecular and Cellular Pharmacology

JF - Molecular and Cellular Pharmacology

SN - 1938-1247

IS - 2

ER -