Nonsurgical Treatment of Aseptic Periprosthetic Gout Flare of the Knee

Foster Chen, Christopher Glezos, Yossef Blum, Michael Hossack, Evan M. Schwechter

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Case: Gout is a rarely reported cause of a painful knee following total knee arthroplasty, but it can mimic infection in its symptomatology and workup. Two individuals who had previously undergone a knee replacement and had a history of gout had symptoms of infection. These patients presented with knee warmth and effusion, and they had elevated inflammatory markers and synovial cell counts. In both cases, there was a good response to medication, and surgery was avoided. Conclusion: Although simultaneous infection can occur, aseptic periprosthetic gout should be considered in individuals with a known history of gout, in those with a good response to anti-gout medication, and when there is an otherwise negative workup for infection.

Original languageEnglish (US)
Article numbere93
JournalJBJS Case Connector
Issue number4
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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