Nonsurgical Treatment of Aseptic Periprosthetic Gout Flare of the Knee

Foster Chen, Christopher Glezos, Yossef Blum, Michael D. Hossack, Evan M. Schwechter

Research output: Contribution to journalArticle

Abstract

Case: Gout is a rarely reported cause of a painful knee following total knee arthroplasty, but it can mimic infection in its symptomatology and workup. Two individuals who had previously undergone a knee replacement and had a history of gout had symptoms of infection. These patients presented with knee warmth and effusion, and they had elevated inflammatory markers and synovial cell counts. In both cases, there was a good response to medication, and surgery was avoided. Conclusion: Although simultaneous infection can occur, aseptic periprosthetic gout should be considered in individuals with a known history of gout, in those with a good response to anti-gout medication, and when there is an otherwise negative workup for infection.

Original languageEnglish (US)
Article numbere93
JournalJBJS Case Connector
Volume6
Issue number4
DOIs
StatePublished - 2016

Fingerprint

Gout
Knee
Infection
Therapeutics
Knee Replacement Arthroplasties
Cell Count

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Nonsurgical Treatment of Aseptic Periprosthetic Gout Flare of the Knee. / Chen, Foster; Glezos, Christopher; Blum, Yossef; Hossack, Michael D.; Schwechter, Evan M.

In: JBJS Case Connector, Vol. 6, No. 4, e93, 2016.

Research output: Contribution to journalArticle

@article{0be5ff0b014746ac93fba4e2526798e9,
title = "Nonsurgical Treatment of Aseptic Periprosthetic Gout Flare of the Knee",
abstract = "Case: Gout is a rarely reported cause of a painful knee following total knee arthroplasty, but it can mimic infection in its symptomatology and workup. Two individuals who had previously undergone a knee replacement and had a history of gout had symptoms of infection. These patients presented with knee warmth and effusion, and they had elevated inflammatory markers and synovial cell counts. In both cases, there was a good response to medication, and surgery was avoided. Conclusion: Although simultaneous infection can occur, aseptic periprosthetic gout should be considered in individuals with a known history of gout, in those with a good response to anti-gout medication, and when there is an otherwise negative workup for infection.",
author = "Foster Chen and Christopher Glezos and Yossef Blum and Hossack, {Michael D.} and Schwechter, {Evan M.}",
year = "2016",
doi = "10.2106/JBJS.CC.16.00076",
language = "English (US)",
volume = "6",
journal = "JBJS Case Connector",
issn = "2160-3251",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Nonsurgical Treatment of Aseptic Periprosthetic Gout Flare of the Knee

AU - Chen, Foster

AU - Glezos, Christopher

AU - Blum, Yossef

AU - Hossack, Michael D.

AU - Schwechter, Evan M.

PY - 2016

Y1 - 2016

N2 - Case: Gout is a rarely reported cause of a painful knee following total knee arthroplasty, but it can mimic infection in its symptomatology and workup. Two individuals who had previously undergone a knee replacement and had a history of gout had symptoms of infection. These patients presented with knee warmth and effusion, and they had elevated inflammatory markers and synovial cell counts. In both cases, there was a good response to medication, and surgery was avoided. Conclusion: Although simultaneous infection can occur, aseptic periprosthetic gout should be considered in individuals with a known history of gout, in those with a good response to anti-gout medication, and when there is an otherwise negative workup for infection.

AB - Case: Gout is a rarely reported cause of a painful knee following total knee arthroplasty, but it can mimic infection in its symptomatology and workup. Two individuals who had previously undergone a knee replacement and had a history of gout had symptoms of infection. These patients presented with knee warmth and effusion, and they had elevated inflammatory markers and synovial cell counts. In both cases, there was a good response to medication, and surgery was avoided. Conclusion: Although simultaneous infection can occur, aseptic periprosthetic gout should be considered in individuals with a known history of gout, in those with a good response to anti-gout medication, and when there is an otherwise negative workup for infection.

UR - http://www.scopus.com/inward/record.url?scp=84996549473&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84996549473&partnerID=8YFLogxK

U2 - 10.2106/JBJS.CC.16.00076

DO - 10.2106/JBJS.CC.16.00076

M3 - Article

C2 - 29252747

AN - SCOPUS:84996549473

VL - 6

JO - JBJS Case Connector

JF - JBJS Case Connector

SN - 2160-3251

IS - 4

M1 - e93

ER -