Noncardiac surgery in heart transplant recipients in the cyclosporine era

Jose A. Melendez, Ellise S. Delphin, Joanne Lamb, Eric Rose

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

As survival and quality of life continue to improve for cardiac transplant recipients, there is an ever-increasing possibility that these patients will present for elective and/or emergency surgery outside of a transplantation center. Cyclosporine therapy has been a major factor in extending homograft survival, but recent studies have suggested that cyclosporine administration increases the duration of action of some anesthetics. The authors evaluated the influence on anesthetic management of cardiac transplantation and chronic cyclosporine therapy in a retrospective review of all postcardiac transplant patients who presented for noncardiac surgery at the study institution. The data suggest that a number of commonly used anesthetic techniques can be administered safely to these patients when no evidence of graft rejection is present. No clinically significant prolongation of anesthetic effect was encountered following the doses of anesthetics described.

Original languageEnglish (US)
Pages (from-to)218-220
Number of pages3
JournalJournal of Cardiothoracic and Vascular Anesthesia
Volume5
Issue number3
DOIs
StatePublished - 1991
Externally publishedYes

Fingerprint

Cyclosporine
Thoracic Surgery
Anesthetics
Graft Rejection
Heart Transplantation
Allografts
Emergencies
Transplantation
Quality of Life
Transplant Recipients
Transplants
Survival
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Noncardiac surgery in heart transplant recipients in the cyclosporine era. / Melendez, Jose A.; Delphin, Ellise S.; Lamb, Joanne; Rose, Eric.

In: Journal of Cardiothoracic and Vascular Anesthesia, Vol. 5, No. 3, 1991, p. 218-220.

Research output: Contribution to journalArticle

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