Noncardiac surgery in heart transplant recipients in the cyclosporine era

Jose A. Melendez, Ellise Delphin, Joanne Lamb, Eric Rose

Research output: Contribution to journalArticle

27 Scopus citations


As survival and quality of life continue to improve for cardiac transplant recipients, there is an ever-increasing possibility that these patients will present for elective and/or emergency surgery outside of a transplantation center. Cyclosporine therapy has been a major factor in extending homograft survival, but recent studies have suggested that cyclosporine administration increases the duration of action of some anesthetics. The authors evaluated the influence on anesthetic management of cardiac transplantation and chronic cyclosporine therapy in a retrospective review of all postcardiac transplant patients who presented for noncardiac surgery at the study institution. The data suggest that a number of commonly used anesthetic techniques can be administered safely to these patients when no evidence of graft rejection is present. No clinically significant prolongation of anesthetic effect was encountered following the doses of anesthetics described.

Original languageEnglish (US)
Pages (from-to)218-220
Number of pages3
JournalJournal of Cardiothoracic and Vascular Anesthesia
Issue number3
Publication statusPublished - Jun 1991
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Anesthesiology and Pain Medicine

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