Non-reciprocal postsynaptic inhibition of digastric motoneurons

Cristina Pedroarena; Pablo Castillo; Michael H. Chase; Francisco R. Morales

doi:10.1016/0006-8993(90)91621-M

Non-reciprocal postsynaptic inhibition of digastric motoneurons

Cristina Pedroarena, Pablo Castillo, Michael H. Chase, Francisco R. Morales

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

This study was undertaken to explore the effects, on digastric motoneurons, of electrical stimulation of a site within the parvocellular medullary reticular formation (PcRF). This site is located lateral to the hypoglossal nucleus and ventral to the dorsal motor nucleus of the vagus nerve. Within this site are somas of premotor interneurons that project to trigeminal motor nuclei^10,13. Stimulation of this site resulted in the generation of IPSPs in digastric motoneurons. We postulate that these IPSPs were due to the activation of a monosynaptic path from the PcRF to digastric motoneurons. The present results, in conjunction with those previously reported which indicate that the PcRF also induces monosynaptic IPSPs in masseter motoneurons², demonstrate that this is a site of origin for the postsynaptic inhibitory control of motoneurons that innervate both jaw opening and closing muscles.

Original language	English (US)
Pages (from-to)	339-342
Number of pages	4
Journal	Brain research
Volume	535
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(90)91621-M
State	Published - Dec 10 1990
Externally published	Yes

Keywords

Digastric
Medulla
Motoneuron
Parvocellularis
Postsynaptic inhibition
Reticular formation

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(90)91621-M

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title = "Non-reciprocal postsynaptic inhibition of digastric motoneurons",

abstract = "This study was undertaken to explore the effects, on digastric motoneurons, of electrical stimulation of a site within the parvocellular medullary reticular formation (PcRF). This site is located lateral to the hypoglossal nucleus and ventral to the dorsal motor nucleus of the vagus nerve. Within this site are somas of premotor interneurons that project to trigeminal motor nuclei10,13. Stimulation of this site resulted in the generation of IPSPs in digastric motoneurons. We postulate that these IPSPs were due to the activation of a monosynaptic path from the PcRF to digastric motoneurons. The present results, in conjunction with those previously reported which indicate that the PcRF also induces monosynaptic IPSPs in masseter motoneurons2, demonstrate that this is a site of origin for the postsynaptic inhibitory control of motoneurons that innervate both jaw opening and closing muscles.",

keywords = "Digastric, Medulla, Motoneuron, Parvocellularis, Postsynaptic inhibition, Reticular formation",

author = "Cristina Pedroarena and Pablo Castillo and Chase, {Michael H.} and Morales, {Francisco R.}",

year = "1990",

month = dec,

day = "10",

doi = "10.1016/0006-8993(90)91621-M",

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pages = "339--342",

journal = "Brain Research",

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T1 - Non-reciprocal postsynaptic inhibition of digastric motoneurons

AU - Pedroarena, Cristina

AU - Castillo, Pablo

AU - Chase, Michael H.

AU - Morales, Francisco R.

PY - 1990/12/10

Y1 - 1990/12/10

N2 - This study was undertaken to explore the effects, on digastric motoneurons, of electrical stimulation of a site within the parvocellular medullary reticular formation (PcRF). This site is located lateral to the hypoglossal nucleus and ventral to the dorsal motor nucleus of the vagus nerve. Within this site are somas of premotor interneurons that project to trigeminal motor nuclei10,13. Stimulation of this site resulted in the generation of IPSPs in digastric motoneurons. We postulate that these IPSPs were due to the activation of a monosynaptic path from the PcRF to digastric motoneurons. The present results, in conjunction with those previously reported which indicate that the PcRF also induces monosynaptic IPSPs in masseter motoneurons2, demonstrate that this is a site of origin for the postsynaptic inhibitory control of motoneurons that innervate both jaw opening and closing muscles.

AB - This study was undertaken to explore the effects, on digastric motoneurons, of electrical stimulation of a site within the parvocellular medullary reticular formation (PcRF). This site is located lateral to the hypoglossal nucleus and ventral to the dorsal motor nucleus of the vagus nerve. Within this site are somas of premotor interneurons that project to trigeminal motor nuclei10,13. Stimulation of this site resulted in the generation of IPSPs in digastric motoneurons. We postulate that these IPSPs were due to the activation of a monosynaptic path from the PcRF to digastric motoneurons. The present results, in conjunction with those previously reported which indicate that the PcRF also induces monosynaptic IPSPs in masseter motoneurons2, demonstrate that this is a site of origin for the postsynaptic inhibitory control of motoneurons that innervate both jaw opening and closing muscles.

KW - Digastric

KW - Medulla

KW - Motoneuron

KW - Parvocellularis

KW - Postsynaptic inhibition

KW - Reticular formation

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DO - 10.1016/0006-8993(90)91621-M

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AN - SCOPUS:0025252442

SN - 0006-8993

VL - 535

SP - 339

EP - 342

JO - Brain Research

JF - Brain Research

IS - 2

ER -

Non-reciprocal postsynaptic inhibition of digastric motoneurons

Abstract

Keywords

ASJC Scopus subject areas

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