Non-reciprocal postsynaptic inhibition of digastric motoneurons

Cristina Pedroarena, Pablo Castillo, Michael H. Chase, Francisco R. Morales

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

This study was undertaken to explore the effects, on digastric motoneurons, of electrical stimulation of a site within the parvocellular medullary reticular formation (PcRF). This site is located lateral to the hypoglossal nucleus and ventral to the dorsal motor nucleus of the vagus nerve. Within this site are somas of premotor interneurons that project to trigeminal motor nuclei10,13. Stimulation of this site resulted in the generation of IPSPs in digastric motoneurons. We postulate that these IPSPs were due to the activation of a monosynaptic path from the PcRF to digastric motoneurons. The present results, in conjunction with those previously reported which indicate that the PcRF also induces monosynaptic IPSPs in masseter motoneurons2, demonstrate that this is a site of origin for the postsynaptic inhibitory control of motoneurons that innervate both jaw opening and closing muscles.

Original languageEnglish (US)
Pages (from-to)339-342
Number of pages4
JournalBrain research
Volume535
Issue number2
DOIs
StatePublished - Dec 10 1990
Externally publishedYes

Keywords

  • Digastric
  • Medulla
  • Motoneuron
  • Parvocellularis
  • Postsynaptic inhibition
  • Reticular formation

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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