Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy

Zhiyi Liu, Eugen Dhimolea, Antonio Varone, Constantine S. Mitsiades, Irene Georgakoudi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report a non-invasive method, which quantifies optical redox ratio and mitochondrial organization via two-photon excited fluorescence microscopy, and apply it to the characterization of metabolic drug effects on breast cancer cell spheroids.

Original languageEnglish (US)
Title of host publicationOptical Molecular Probes, Imaging and Drug Delivery, OMP 2017
PublisherOSA - The Optical Society
ISBN (Electronic)9781557528209
DOIs
StatePublished - 2017
Externally publishedYes
EventOptical Molecular Probes, Imaging and Drug Delivery, OMP 2017 - San Diego, United States
Duration: Apr 2 2017Apr 5 2017

Publication series

NameOptics InfoBase Conference Papers
VolumePart F63-OMP 2017

Conference

ConferenceOptical Molecular Probes, Imaging and Drug Delivery, OMP 2017
Country/TerritoryUnited States
CitySan Diego
Period4/2/174/5/17

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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