Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy

Zhiyi Liu; Eugen Dhimolea; Antonio Varone; Constantine S. Mitsiades; Irene Georgakoudi

doi:10.1364/OMP.2017.OmM4D.2

Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy

Zhiyi Liu, Eugen Dhimolea, Antonio Varone, Constantine S. Mitsiades, Irene Georgakoudi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We report a non-invasive method, which quantifies optical redox ratio and mitochondrial organization via two-photon excited fluorescence microscopy, and apply it to the characterization of metabolic drug effects on breast cancer cell spheroids.

Original language	English (US)
Title of host publication	Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017
Publisher	Optica Publishing Group (formerly OSA)
ISBN (Print)	9781943580255
DOIs	https://doi.org/10.1364/OMP.2017.OmM4D.2
State	Published - 2017
Externally published	Yes
Event	Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017 - San Diego, United States Duration: Apr 2 2017 → Apr 5 2017

Publication series

Name	Optics InfoBase Conference Papers
Volume	Part F63-OMP 2017
ISSN (Electronic)	2162-2701

Conference

Conference	Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017
Country/Territory	United States
City	San Diego
Period	4/2/17 → 4/5/17

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Mechanics of Materials

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1364/OMP.2017.OmM4D.2

Cite this

Liu, Z., Dhimolea, E., Varone, A., Mitsiades, C. S., & Georgakoudi, I. (2017). Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy. In Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017 (Optics InfoBase Conference Papers; Vol. Part F63-OMP 2017). Optica Publishing Group (formerly OSA). https://doi.org/10.1364/OMP.2017.OmM4D.2

Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy. / Liu, Zhiyi; Dhimolea, Eugen; Varone, Antonio et al.
Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017. Optica Publishing Group (formerly OSA), 2017. (Optics InfoBase Conference Papers; Vol. Part F63-OMP 2017).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Liu, Z, Dhimolea, E, Varone, A, Mitsiades, CS & Georgakoudi, I 2017, Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy. in Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017. Optics InfoBase Conference Papers, vol. Part F63-OMP 2017, Optica Publishing Group (formerly OSA), Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017, San Diego, United States, 4/2/17. https://doi.org/10.1364/OMP.2017.OmM4D.2

Liu Z, Dhimolea E, Varone A, Mitsiades CS, Georgakoudi I. Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy. In Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017. Optica Publishing Group (formerly OSA). 2017. (Optics InfoBase Conference Papers). doi: 10.1364/OMP.2017.OmM4D.2

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title = "Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy",

abstract = "We report a non-invasive method, which quantifies optical redox ratio and mitochondrial organization via two-photon excited fluorescence microscopy, and apply it to the characterization of metabolic drug effects on breast cancer cell spheroids.",

author = "Zhiyi Liu and Eugen Dhimolea and Antonio Varone and Mitsiades, {Constantine S.} and Irene Georgakoudi",

note = "Publisher Copyright: {\textcopyright} 2017 OSA.; Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017 ; Conference date: 02-04-2017 Through 05-04-2017",

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doi = "10.1364/OMP.2017.OmM4D.2",

language = "English (US)",

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AU - Georgakoudi, Irene

PY - 2017

Y1 - 2017

N2 - We report a non-invasive method, which quantifies optical redox ratio and mitochondrial organization via two-photon excited fluorescence microscopy, and apply it to the characterization of metabolic drug effects on breast cancer cell spheroids.

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AN - SCOPUS:85032263155

SN - 9781943580255

T3 - Optics InfoBase Conference Papers

BT - Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017

PB - Optica Publishing Group (formerly OSA)

T2 - Optical Molecular Probes, Imaging and Drug Delivery, OMP 2017

Y2 - 2 April 2017 through 5 April 2017

ER -

Non-invasive characterization of metabolic drug effects on breast cancer cell spheroids using two-photon excited fluorescence microscopy

Abstract

Publication series

Conference

ASJC Scopus subject areas

UN SDGs

Access to Document

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