Nitric oxide treatment for pulmonary hypertension after neonatal cardiac operation

Aamir S. Shah, Arthur J. Smerling, Jan M. Quaegebeur, Robert E. Michler

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This report describes a newborn with transposition of the great arteries who underwent a Blalock-Taussig shunt with transient improvement in oxygenation, but required emergent insertion of a central shunt later the same day due to progressive hypoxia and cardiac arrest. Two hours after central shunt insertion, sudden episodes of hypoxia and hypotension developed that were resistant to all pharmocologic therapy. Inhaled nitric oxide (25 ppm) was then administered with dramatic improvement in oxygenation and hemodynamics within minutes. The patient's condition stabilized after these measures, and nitric oxide therapy was discontinued after 2 days.

Original languageEnglish (US)
Pages (from-to)1791-1793
Number of pages3
JournalThe Annals of thoracic surgery
Volume60
Issue number6
DOIs
StatePublished - 1995
Externally publishedYes

Fingerprint

Pulmonary Hypertension
Nitric Oxide
Blalock-Taussig Procedure
Transposition of Great Vessels
Heart Arrest
Hypotension
Hemodynamics
Newborn Infant
Therapeutics
Hypoxia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery

Cite this

Nitric oxide treatment for pulmonary hypertension after neonatal cardiac operation. / Shah, Aamir S.; Smerling, Arthur J.; Quaegebeur, Jan M.; Michler, Robert E.

In: The Annals of thoracic surgery, Vol. 60, No. 6, 1995, p. 1791-1793.

Research output: Contribution to journalArticle

Shah, Aamir S. ; Smerling, Arthur J. ; Quaegebeur, Jan M. ; Michler, Robert E. / Nitric oxide treatment for pulmonary hypertension after neonatal cardiac operation. In: The Annals of thoracic surgery. 1995 ; Vol. 60, No. 6. pp. 1791-1793.
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